Point-and-click adventures?

Any recommendations of modern or not so modern point-and-click adventures (for PC)? Just finished all of Wadjet Eyes games (loved Blackwell series!) and I'm craving some good stuff. I'm interested in not-orthodox games too if there's some experimental stuff that you like. Are the telltale games worth it? I'm also tempted by the Sherlock Holmes games.

Incidentally, any advice on how to find (and make work) some old(ish) adventures? In particular looking for Discworld II and Noir, EcoQuest, Simon the Sorcerer, Hollywood Monsters, Runaway, or the older (EA I think) Sherlock Holmes games (they are not in GOG I think).

Extra bonus points if there's a way to make them work in Mac and Linux!