The silver lining of this pandemic is that medicine is about to pop off if even a few of these mRNA treatments hold water. It maybe only a matter of time before we can deal with all sorts of heart...
The silver lining of this pandemic is that medicine is about to pop off if even a few of these mRNA treatments hold water. It maybe only a matter of time before we can deal with all sorts of heart disease and autoimmune stuff, and maybe, finally, change the math on whether the owner of a lonely heart is better off than the owner of a broken heart.
A very intriguing combination of mRNA vaccine technology & CAR-T cell therapy! I will have to keep an eye out for more work from this research group, see if their work manages to progress beyond...
A very intriguing combination of mRNA vaccine technology & CAR-T cell therapy! I will have to keep an eye out for more work from this research group, see if their work manages to progress beyond the animal model stage ( where so many interesting ideas die, sadly...).
Immune cells in the bodies of mice have been temporarily reprogrammed to repair damaged hearts by removing scar tissue, thanks to the technology used in the mRNA coronavirus vaccines.
“After you give the treatment, the scar goes away,” says Haig Aghajanian at the University of Pennsylvania.
Genetically engineered immune cells called CAR T-cells are already being used to treat cancer, but this is extremely expensive. The mRNA approach, which involves only temporarily modifying these cells, could dramatically decrease costs.
“CAR-T therapy has been a breakthrough, but it costs a lot,” says Aghajanian. “We’re hoping this is the next step in CAR-T-type technology that will allow more access. This type of thing you can get to developing countries, to remote areas.”
The silver lining of this pandemic is that medicine is about to pop off if even a few of these mRNA treatments hold water. It maybe only a matter of time before we can deal with all sorts of heart disease and autoimmune stuff, and maybe, finally, change the math on whether the owner of a lonely heart is better off than the owner of a broken heart.
A very intriguing combination of mRNA vaccine technology & CAR-T cell therapy! I will have to keep an eye out for more work from this research group, see if their work manages to progress beyond the animal model stage ( where so many interesting ideas die, sadly...).
From the article: