29 votes

Study of 500,000 medical records links viruses with Alzheimer's again and again

4 comments

  1. [4]
    chocobean
    Link
    So....get your viral vaccines, can't hurt, and may even be beneficial in other ways? From a brief Google search it sounds like there are more people per million with dementia in countries with...

    So....get your viral vaccines, can't hurt, and may even be beneficial in other ways?

    From a brief Google search it sounds like there are more people per million with dementia in countries with free vaccine than US... There's a long road before we understand anything like enough

    8 votes
    1. [3]
      hattar
      Link Parent
      I’m definitely not an anti-vax person, got both flu and Covid this week. That said, why wouldn’t we suspect the same mechanism to exist in both the virus and the vaccine to bring out Alzheimer’s?...

      I’m definitely not an anti-vax person, got both flu and Covid this week.

      That said, why wouldn’t we suspect the same mechanism to exist in both the virus and the vaccine to bring out Alzheimer’s? Viruses and vaccines are inherently similar. Seems like we know little enough that this isn’t yet actionable info.

      2 votes
      1. whbboyd
        Link Parent
        I cannot overstate this: they really, really are not. Viruses directly attack the body biochemically. They destroy cells; integrate themselves into cells long-term, with various followon effects;...

        Viruses and vaccines are inherently similar.

        I cannot overstate this: they really, really are not.

        Viruses directly attack the body biochemically. They destroy cells; integrate themselves into cells long-term, with various followon effects; leave behind all manner of chemical detritus; can sometimes leave permanent genetic changes in infected cells. You get illness symptoms from viral infections in significant part because they are literally causing damage to your body.

        Vaccines do… none of that. The whole point of a vaccine is to expose your body to immunity-generating antigens without causing all the accessory harm that an actual viral infection would. The immune reaction can be symptomatic (which is why people often feel blah the day after a vaccination), but this is just because some immune reactions (e.g. fever) are unpleasant; there's no damage happening.


        Now, to be clear and pre-address a possible objection, there are two broad exceptions to the "vaccines are inert" statement. The first is Jenner's cowpox, which is a literal disease (just a much, much less serious one than smallpox). To my knowledge, we don't use any vaccines of this class today. (They're highly circumstantial, anyway; you need an extant, related, non-virulent variant of the disease you're trying to prevent.) The second is "live attenuated" vaccines, which do contain active virus particles, but no longer infect human cells to any significant degree.

        17 votes
      2. PelagiusSeptim
        Link Parent
        From the article: "Although vaccines do not prevent all cases of illness, they are known to dramatically reduce hospitalization rates. This evidence suggests that vaccination may mitigate some...

        From the article: "Although vaccines do not prevent all cases of illness, they are known to dramatically reduce hospitalization rates. This evidence suggests that vaccination may mitigate some risk of developing neurodegenerative disease."

        It seems the alzheimer's cases are specifically linked to virus hospitalizations, not all infections and certainly not just from vaccinations.

        13 votes