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15 votes
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We should take hantavirus more seriously
33 votes -
When Richard Dawkins met Claude
22 votes -
Most US doctors are quietly using the OpenEvidence AI tool. Few patients know about it.
15 votes -
Hi, how are you? Mental health support and discussion thread (May 2026)
This is a monthly thread for those who need it. Vent, share your experiences, ask for advice, talk about how you are doing. Let's make this a compassionate space for all who may need one.
24 votes -
Lost/losing the drive for friendship
I'm in my mid 20s and have had a pretty lonely life. I had a very lonely childhood, a less lonely but still fairly lonely adolescence, and again a very lonely time in college (in that case,...
I'm in my mid 20s and have had a pretty lonely life. I had a very lonely childhood, a less lonely but still fairly lonely adolescence, and again a very lonely time in college (in that case, because of a mix of mental hangups, the pandemic, personal circumstance that was a major drain on my time, and not managing all those things as optimally as I could have). At this point in my life, I essentially only have one friend, who I met a couple years ago and has since moved across the country.
I have more time on my hands now, am probably more socially adept than I used to be, but I find myself having lost or losing the drive to make friends. I guess I've gone so long without friends that I've lost sense at an emotional level of what the point even is. It's also friggin hard to meet people in the adult world and it seems like you have to put twice the energy to meet people that you vibe with half as much as when you were younger. I want to want to make friends, but it feels like I'd be setting myself up for more pain and disappointment by putting myself in that headspace. It also doesn't help that I'm pretty socially picky (not in a judgmental way, but I'd prefer a small circle of people I'm really close with over a large group that I'm not) and that I have a strong need to feel like the friends I make aren't "arbitrary", that they are the ones I am "meant" to be around. Has anyone experienced something similar or have any advice?
48 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
3 votes -
A screen addict on the couch
13 votes -
World's first vaccine for Lyme disease could be available in 2027
25 votes -
Hi, how are you? Mental health support and discussion thread (July 2025)
This is a monthly thread for those who need it. Vent, share your experiences, ask for advice, talk about how you are doing. Let's make this a compassionate space for all who may need one.
20 votes -
Vegetative patients may be more aware than we knew (gifted link)
25 votes -
Health Canada approves 1st generic version of Novo Nordisk's Ozempic
40 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
6 votes -
I have a spondylolisthesis diagnosis
I had been having pain in my "upper butt" when sitting for a few weeks, so I went to an orthopedic practice that has urgent care walk in hours. He diagnosed it as sacroiliac inflammation and gave...
I had been having pain in my "upper butt" when sitting for a few weeks, so I went to an orthopedic practice that has urgent care walk in hours. He diagnosed it as sacroiliac inflammation and gave me an anti-inflammatory (meloxicam) and a PT script. The PT did not have an opening until week after next, but the medicine has has really helped with the pain.
Them took xrays during my visit, and the side-looking one shows spondylolisthesis (one of my lumbar vertebrae has slipped forward). He pointed it out (casually) and didn't say much about it other than he thought it wasn't the cause of my pain. Maybe he thought I already knew about it?
I have been having lower back pain off and on for a long time. I went to my doctor one time, and he diagnosed it as a bulging disc. He had given me some meloxicam and strengthening exercises to do at home. Since then, I would have pain in my lower back intermittently as well as occasional numbness in my leg, but I had just assumed it was a disc and tried to keep strengthening my core.
I am overweight (280lb) and not very active (software engineer). I started a new job that is in office this year, so I'm a lot less sedentary than I was working from home. I have a fantastic yoga teacher, and I do that every week. My practice in between classes has been intermittent at best, but I am trying to make it more regular.
Right now, I'm waiting for the PT to start, and I have a followup appointment with the spine specialist at the ortho in a fee weeks.
My biggest problem is that whenever I think about the xray, and seeing that disc so misaligned, my anxiety really spikes to 11. I get the "heebie jeebies", the same creepy shivering feeling I get if a bug unexpectedly crawls on me. It's happening most days. I feel kind of betrayed by my body.
I have talked to my therapist about the anxiety, and we are working on it. But in the mean time it is very stressful and distracting.
If you made it this far, thank you for reading. I am not sure what I'm really asking for. There's plenty of information online about the treatments. I guess I am wondering if other people went through it, how did it affect your mobility, quality of life, etc? Are there things you wish you had known?
Honestly, I think I could just use a (virtual) hug.
30 votes -
Pharmacogenetics personalised medicine: new frontier or nonsense?
Apparently my private health insurance covers pharmacogenetics testing to find the best ADHD medication. What is it, is it legit? What's the company going to do with my cheek swabs? How do doctors...
Apparently my private health insurance covers pharmacogenetics testing to find the best ADHD medication. What is it, is it legit? What's the company going to do with my cheek swabs? How do doctors feel about me going up to them and say hey internet pharma bro tells me I should be taking this instead of what your years of medical school thinks.
What I can't figure out is how my insurance company benefits from this. I'm not paying extra for this service so I must be the product right? Here's part of the
marketingFAQ info from my insurance provider:Personalized Medicine uses advanced pharmacogenetic testing and pharmacist assistance to find the most effective medication for you.
If you’re starting a new medication for a mental health condition (such as anxiety or depression), chronic pain, attention deficit hyperactivity disorder (ADHD), or neurological conditions – or taking a medication for one of these conditions and it’s not working or causing side effects – Personalized Medicine could help. It’s offered through your extended health care benefits plan, so the cost of the test may be covered. To see the list of drugs tested, click here.
It involves a pharmacogenetic test. This is a type of test that identifies how you may respond to medications. Your test results are only for you and anyone you give consent to share them with, such as your doctor. The test is run by Personalized Prescribing Inc., a Canadian company. Manulife
(Forgot to mention this is for a Canadian employment extended health insurance.)
15 votes -
For those who deal with hypoglycemia, do you have any advice for dealing with fatigue after a bad low?
My hypoglycemia issues are not related to diabetes fwiw. That said, I tend to get hypoglycemia a few times a day. If I catch it quick enough and treat, it's usually not a big deal, but if I get...
My hypoglycemia issues are not related to diabetes fwiw. That said, I tend to get hypoglycemia a few times a day. If I catch it quick enough and treat, it's usually not a big deal, but if I get too low (maybe once I get into the 50s mg/dl), then after treating (usually about 15 minutes later), I get so. freaking. tired. Like, barely able to stand up exhausted. Currently dealing with this as we speak, and it's very frustrating. My endocrinologist told me it's normal to get tired like this while recovering. I'm curious if anyone else deals with this? If so, do you have any advice for dealing with the fatigue?
Tildes might be too small of a platform for this. If no one deals with hypoglycemia here, please feel free to remove it. I thought with the prevalence of diabetes, it would be likely there are folks who encounter this.
EDIT: In case anyone ever stumbles on this, turns out it was an insulinoma. I finally had surgery. Don't give up hope, answers can be out there, even if you feel like there's no where left to look.
13 votes -
Polish influencer breaks charity streaming record, raising 59 million euros for cancer treatment
19 votes -
So it turns out I was cheated on
Some of you may remember me from another thread, where I hemmed and hawed and fretted my way through trying to navigate my struggling relationship. I thought I'd reached the final chapter, I moved...
Some of you may remember me from another thread, where I hemmed and hawed and fretted my way through trying to navigate my struggling relationship. I thought I'd reached the final chapter, I moved out and established a place for my child and myself. I cut as many ties as I could with my now ex, but of course several threads still remain.
Yesterday (April Fools of course) I found out that they had been cheating on me since last May, at least. Potentially longer. Of course, I'm devastated. I knew they had found someone else already recently, but I thought it was in the last month or two. This new piece of the puzzle has solved so many unanswered questions I've had, while also creating many new ones.
I feel used, financially/emotionally abused, gaslit, and more. I'm still working on processing everything. I'm trying to remain calm for the sake of the kids (especially mine) but it's really, really hard. I know it isn't a reflection on me - I tried everything I could to fix things. It is hard however not feel that utter sense of betrayal in my gut and soul like a knife.
What resources, reading, supports, guides are there for this? I'm just trying to get through today and then I have a three day weekend to work on processing this all.
68 votes -
Planned Parenthood is turning to services like Botox to stay afloat
18 votes -
How US doctors cashed in on the No Surprises Act
27 votes -
Hi, how are you? Mental health support and discussion thread (April 2026)
This is a monthly thread for those who need it. Vent, share your experiences, ask for advice, talk about how you are doing. Let's make this a compassionate space for all who may need one.
22 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
4 votes -
Guinea worm disease reaches all-time low: only ten human cases reported in 2025
27 votes -
World's top condom maker Karex to raise prices sharply as Iran war strains supply chain
17 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
5 votes -
The cosmetic industry’s new frontier: cadaver fat
19 votes -
Am I German or autistic?
74 votes -
Competence is lonely. Nobody talks about why.
74 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
9 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
8 votes -
How to tolerate annoying things
29 votes -
Ozempic is about to go generic in India, China and Canada
39 votes -
Vaping likely to cause lung and oral cancer, Australian researchers find in new review of evidence
42 votes -
AI software for smart glasses wins £1m prize for technology to help people with dementia
10 votes -
How cash is helping Kenyan moms access care
15 votes -
Meta and YouTube found liable in landmark social media addiction trial
53 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
5 votes -
"People are turning themselves into lab rats" – the injectable peptides craze sweeping the US
33 votes -
Opinions wanted on regular DEXA scans
I’ve gone a bit too deep on a rabbit hole after an offhand comment about protein intake and how much protein I should actually be consuming. It turns out that the 1.6g/kg of body weight is fairly...
I’ve gone a bit too deep on a rabbit hole after an offhand comment about protein intake and how much protein I should actually be consuming. It turns out that the 1.6g/kg of body weight is fairly arbitrary and body weight itself is not a particularly good point to use for an estimate if you are overweight. With that in mind I have been wondering about getting a DEXA body composition scan. It would be useful, I think, because it can also tell me about visceral fat which is an area I am particularly concerned about.
It turns out that it’s pretty cheap to get done; about $45 if you sign up for quarterly scans with a company called BodySpec. Their whole thing is making things cheaper by having repeat visits; a quantity discount, if you will.
Before I decide to do this (and while I wait to hear back about if I can get one done for free with my health plan), I just wanted to get people’s opinions on them. Have you had one or a series done? And more importantly, how has it empowered you to improve your health?
In all honesty I’m not sure the results will encourage me to make any particular change in my lifestyle or routine that I wouldn’t have been able to figure out without it.
7 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
11 votes -
Lyme disease vaccine shows seventy percent efficacy, Pfizer says
45 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
8 votes -
Your daily coffee may be protecting your brain, 43-year study finds
33 votes -
The miracle cure for sickle cell is now two years old. Most Americans are still waiting.
9 votes -
Woman diagnosed with sickle cell at two months old wakes up without pain for the first time after new treatment
18 votes -
Hi, how are you? Mental health support and discussion thread (March 2026)
This is a monthly thread for those who need it. Vent, share your experiences, ask for advice, talk about how you are doing. Let's make this a compassionate space for all who may need one.
28 votes -
I need to talk to someone with social mobility experience, and I'm out of ideas
Sorry this is pretty rant-y, I tried I promise lol: I've posted on here re: topics similar to & leading towards this one, but not in this group specifically, so apologies if this is not the right...
Sorry this is pretty rant-y, I tried I promise lol:
I've posted on here re: topics similar to & leading towards this one, but not in this group specifically, so apologies if this is not the right place but idk where else to put it lol: I need to talk to someone who started life less-well off, whatever that means where you come from, and worked themselves into a better situation, and then actually finally broke through whatever the fuck this is that I can't get past right now.
I am solidly working/lower middle class (low low, like I'm not gonna lose my house but I also could never move, no savings but only overdraft -occasionally-, etc.): education background, higher ed, public service, etc—I got too many degrees & got on some good meds & found out mid-30s I have a lot of marketable transferable high-level skills, setting me on a course to replace all the side gigs with one Good Job. Almost got a couple of -really- good offers (like, verbal, then waiting, then layoffs, then a very disappointing email, rinse and repeat) as it unfortunately just happened to be the worst year to look for a job since 2008 lol.
One of the things I'm good at is talking/listening to people, and one of the things I was lacking in was a good network (the other BA/education grads I knew also don't have very good jobs), so I started talking to anyone & everyone, mostly aspirational/mentor types, they have all done very well for themselves & I think it's self-selectinf but they're all pretty sales-y, which is fine. And as another skill I can usually "spot" people, pattern recognition or maybe autism idk, so I'm only talking to people who have had success but also that I don't anticipate will be telling me to pull myself up by my bootstraps, etc.
So here's the thing: every single one of them has said basically (and I think genuinely trying to be helpful): "Why do you need a better job?", "What do you really want here?", "I had what you're after and it didn't make me happy, it was what you already have that did that for me finally," and so if you are having thoughts like that, thank you for reading, please leave lol, because I just cannot—like of course it's easy for you to say "Oh, a corporate job is just travel & restaurants, that's no way to live" when you've already done it! I want in, dude. And honestly it feels like something a woman in the 80s or 90s would have been up against—like "Oh you're better off where you are," ok sure let's fucking swap then. Jesus.
Ok sorry /rant. So what I need is for someone who grew up pretty low income to tell me that there's even a hope, a shred of a possibility that I can do better for myself & my family, because all I can find is people telling me I should be happy with what I have, and the truth is I am not, I'm spinning my wheels and going insane, I am running at maybe 10% capacity and it's driving me nuts—i can literally hear it now "boy I wish I had that much free time”: yeah? What would you do with it? Expensive shit, I bet. See? I feel like I could have both things, but no one wants to let me in—is it just in-group mentality & self-preservstion? Am I somehow threatening their status quo by being a real life person who could maybe do what they did? Because the closest I've gotten so far is hearing how someone along the way cut them a break & that's how they got their start, except none of them seem to be able to see the irony in saying that to me before telling me to just enjoy it as it comes, take it easy, my god I am going to have an aneurysm. And we're talking a significant sample of probably 15-20 people—is it just boomers? Am I doomed?
The most recent take was: "Well you seem like a person who's comfortable and middle-class, so it'll happen, you're fine." And I'm not, like, giving them the hard sell or asking for a job, I'm just mostly listening. I don't get it, and I don't know what I'm supposed to do when I'm trying to find out how someone got to where they are & they end with "You don't need what I have." Is social mobility even a thing anymore in the US?
Edit: gosh I just want to say how much I love this weird lil site, I am feeling about a million times better than I did this time yesterday, to the point that when the person I spoke with (the one who sent me spiraling & considering just going to bed & not getting out of it lol) messaged me to ask if I'd like to talk some more, I didn't say anything but "I'd love to!" because I didn't have to. Because they don't have to get it, they just have to help me find a job—seems like quite a few of you get it & that's all I think I really need sometimes.
(unless you're hiring then pls lmk lol)
27 votes -
Genetically modified bacteria convert plastic waste into Parkinson's drug
9 votes -
Rescue dog Rosie’s cancer shrinks after world-first mRNA vaccine
32 votes -
They feel bugs inside them. Doctors don't know why.
10 votes