12 votes

A major reversal on aspirin highlights a concept everyone should understand

3 comments

  1. [2]
    Adys
    (edited )
    Link
    OH MY GOD WHAT? I had no idea. Is this true? Those are insane numbers. Every day?! Aspirin has a pretty bad reputation in my book in the first place. Don’t take it unless you very, very explicitly...

    A whopping 29 million Americans take aspirin every single day in order to prevent heart disease.

    OH MY GOD WHAT?

    I had no idea. Is this true? Those are insane numbers. Every day?!

    Aspirin has a pretty bad reputation in my book in the first place. Don’t take it unless you very, very explicitly need the effects of a blood thinner.

    In my childhood it was synonym with painkiller but I would say about 20 years ago it got displaced by paracetamol entirely. I myself have never taken aspirin in my life.

    Edit: that website, The NNT, has near immediately graduated to a reference for me. After browsing it for a bit, it looks fantastic, I’ll be checking it often for future treatments.

    4 votes
    1. skybrian
      Link Parent
      Apparently the most common recommendation was a low dose (81 mg). Still, who knows what people really do. Sometimes people think more is better.

      Apparently the most common recommendation was a low dose (81 mg).

      Still, who knows what people really do. Sometimes people think more is better.

      1 vote
  2. skybrian
    Link
    From the article:

    From the article:

    Medical recommendations change all the time, as knowledge is updated. But I think this case is a particularly teachable moment, highlighting the importance of comparing costs and benefits on the same scale. And there’s an important concept in medicine that can help with that — namely: NNT.

    NNT is an abbreviation for “number needed to treat.” In other words: How many patients must be treated with the drug in order for a single patient to get the desired benefit?

    1 vote