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  • Showing only topics in ~talk with the tag "ama". Back to normal view / Search all groups
    1. A "low-risk" AMA thread for everyone

      Historically, I've found the most interesting AMA's came from seemingly "ordinary" people. (touchmyfuckingcoffee's vacuum AMA's come to mind!) I think that most everyone has one or two life...

      Historically, I've found the most interesting AMA's came from seemingly "ordinary" people. (touchmyfuckingcoffee's vacuum AMA's come to mind!) I think that most everyone has one or two life experiences, points of view, or specialized knowledge that would be fun to share or fun to learn about.

      I've toyed with the idea of hosting an AMA for awhile, but I've been afraid that maybe I wasn't "interesting" enough. Then, I realized that others might be in the same position! So instead of hosting my own AMA, I wanted to make space for a collective "Low-Risk" AMA, that I think would work especially well with Tildes' philosophy and format.

      With that preamble, I'm wondering if you would like to join me in an experiment? Let's make mini-AMA's out of top-level comments, with the Q's and A's as child comments.

      Edit: Wow! I wasn't expecting this thread to have so much staying power! Love all the conversations that are being had. FYI The early posters including myself are still answering questions, so don't be shy!

      191 votes
    2. IAMA 3rd year Ph.D. student researching the cell biology of the Rice Blast fungus, Magnaporthe oryzae, and preparing for my candidacy qualifying exam. AMA.

      Hi Tilders! I am new here, but my experience with the community thus far has encouraged me to post an AMA. I've specifically decided to post this AMA in ~talk rather than ~science for more...

      Hi Tilders! I am new here, but my experience with the community thus far has encouraged me to post an AMA. I've specifically decided to post this AMA in ~talk rather than ~science for more exposure, and because I am hoping to field questions ranging from scientifically well-read to less-read, technical to curious, why care to who cares, and everything in between.

      I won't be posting "verifying proof", because like many of you, I love my anonymity here. However, I will include peer-reviewed citations to question answers when I feel it necessary. I will do my best to share free-access articles, but this won't always be possible. If I link an article of interest to you that is paid-access, message me; maybe, I may be able to get a copy to you. Also, please be patient for my replies. Even though it is summer where I am, I am still busy in the lab and thoughtful responses take time.

      Here is a brief background on the Rice Blast fungus to help get the conversation started:

      Rice is an important staple food consumed by nearly half of the global population Khush. 2005. From 10 - 30% of the annual rice harvest is lost to disease caused by Magnaporthe oryzae, which is enough rice to feed greater than 60 million people Skamnioti and Gurr. 2009. To cause infection, a three-celled asexual spore called a conidium attaches to the rice plant's leaves, stems, and even roots. Once attached, a germ tube emerges from one of the three cells and grows along the surface of the plant. Hydrophobic molecules on the plant surface, called hydrophobins, induce a developmental change in the growing germ tube. The growing germ tube tip begins to form a dome-shaped structure called the appressorium. This specialized structure swells and generates up to 80 Mpa of pressure, enough to penetrate kevlar. A penetration peg penetrates the plant cell tissue, and bulbous invasive hyphae colonize the plant cell tissue. The fungus keeps the invaded plant cell alive, while it consumes its nutrients, with the plant cell dying only when the invading growth moves to an adjacent cell Cruz-Mireles et al. 2021. Schematic.

      The Rice Blast research community focuses on all stages of its development. My work is focused on nuclear division during different developmental stages, and I am specifically working on understanding which and how motor proteins are involved in nuclear division in this fungus. Understanding the nuclear dynamics and the involved machinery will hopefully open avenues for controlling the plant infection and reducing the global crop loss.

      I hope you all find Rice Blast interesting, and I hope I will be able to answer many interesting questions!

      40 votes
    3. I've been on the hair loss drug Dutasteride for two years now. AMA.

      I'll start this post off by summarizing my hair loss experience. When I was 18, a few months shy of 19, I went to the barber and there was a miscommunication and the barber ended up buzzing my...

      I'll start this post off by summarizing my hair loss experience.

      When I was 18, a few months shy of 19, I went to the barber and there was a miscommunication and the barber ended up buzzing my hair off. This is the first time that I was able to see my hairline in a while and I saw that it was higher than I remembered. I was scared at first, I couldn't believe that my hairline was receding. But then I read a few things figures maybe it was just maturing, and then I eventually forgot. Actually a few months later I was back thinking to whether I was losing my hair or not. I talked to a cousin of mine and he said something about a pill that he was taking but that it had a possible side effect of erectile dysfunction. I wasn't going to take a chance on that when I wasn't even sure if I was actually balding.

      The next year and a half, I stop thinking about hair loss. It's like I had my memory wiped of that moment, probably due to stress from school. The only thing that happened is that I thought to myself was "man my hair is kind of weird right now." And also I had developed a scalp issue, which I later found out was psoriasis also due to stress.

      So, right before the pandemic hits in February 2020, me and my dad go have lunch at this restaurant. I take a shower and go out. My hair is still wet by the time we go to the restaurant. My dad looks up at my hair and asks "are you losing your hair?" And that's when I realized that I was indeed going bald. For the next three months, I was going through all the stages of grief. I was wildly depressed and anxious. I did some research into possible treatments. It took me a while to learn (or re-learn) about the pill known as finasteride. I then find out about a website where you can buy prescription meds without a prescription shipped over from India so I buy finasteride from there and I started treatment on May 1st 2020. I was 20 years old. I then go to the dermatologist two months later and they prescribe me Dutasteride which I have been on ever since.

      My initial side effect on the drug was watery semen, which cleared up a few weeks after starting the drug. My hair has re-grown a lot. It's back to it's original thickness, and my hairline has made a rather substantial comeback. It's not all back, but enough to the point where the average person wouldn't know I'm balding anymore.

      Let me know if you have any questions. I would love to post pictures, but I rather not if that's okay with everyone.

      18 votes
    4. Turkey information thread: AmA you're curious about Turkey

      @gergir mentioned the idea, and I thought, why not give it a try? I'm a young adult from Turkey, lived up until now in Istanbul. Whether specific to that city or not, and whether about life,...

      @gergir mentioned the idea, and I thought, why not give it a try?

      I'm a young adult from Turkey, lived up until now in Istanbul. Whether specific to that city or not, and whether about life, tourist attractions, politics, culture, etc., just AmA.

      If you have anything you don't want to publicly ask, I'l love to help if you PM me your question.

      32 votes
    5. Anyone interested in learning a bit more about the Catalan situation? AMA.

      Hey all, I'm Catalan (expat) and many of my friends in the USA or other countries in Europe tend to ask me a lot about the Catalan situation: independence, Puigdemont's extradition, political...

      Hey all,

      I'm Catalan (expat) and many of my friends in the USA or other countries in Europe tend to ask me a lot about the Catalan situation: independence, Puigdemont's extradition, political prisoners, police brutality, etc. I figured maybe some users here will be interested too?

      I consider myself equidistant to both the independentist nationalist, and the centralist nationalist movements (I'm more anti-borders than pro-borders, and I don't recognize the authority of any state), so I figure many of my responses will annoy everybody in Spain equally :-) . That said I would appreciate it if we all keep the discussion civil and as soon as I see flame wars I will stop answering questions.

      To my fellow Spaniards/Catalans. Feel free to chime in, contradict me with facts and opinions (I will probably not argue with you, I'm actually eager to learn more about other points of view in this matter), answer questions that I haven't answered for lack of knowledge, etc. Hell even if you are not from Spain but you know about it feel free to give me your two cents.

      Hope we get interesting discussions and we all learn from this!

      16 votes
    6. I'm Brian. I'm an intellectual property attorney and I moderate some stuff on Reddit, like IAmA. Ask Me Anything.

      Hey! I practice IP law with my brothers in Southern California. I primarily do trademark, copyright and litigation work. My brothers do patents and litigation. I also moderate stuff on Reddit,...

      Hey! I practice IP law with my brothers in Southern California. I primarily do trademark, copyright and litigation work. My brothers do patents and litigation.

      I also moderate stuff on Reddit, like IAmA. Ideally, I'd like to host some AMAs here. This is kind of a test to see how it goes at an early stage.

      Ask me stuff!

      Proof with TruePic

      Edit: This was fun. Thank you guys. I'm headed out for a bit. :)

      22 votes