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  • Showing only topics with the tag "ama". Back to normal view
    1. A "low-risk" AMA thread for everyone

      Historically, I've found the most interesting AMA's came from seemingly "ordinary" people. (touchmyfuckingcoffee's vacuum AMA's come to mind!) I think that most everyone has one or two life...

      Historically, I've found the most interesting AMA's came from seemingly "ordinary" people. (touchmyfuckingcoffee's vacuum AMA's come to mind!) I think that most everyone has one or two life experiences, points of view, or specialized knowledge that would be fun to share or fun to learn about.

      I've toyed with the idea of hosting an AMA for awhile, but I've been afraid that maybe I wasn't "interesting" enough. Then, I realized that others might be in the same position! So instead of hosting my own AMA, I wanted to make space for a collective "Low-Risk" AMA, that I think would work especially well with Tildes' philosophy and format.

      With that preamble, I'm wondering if you would like to join me in an experiment? Let's make mini-AMA's out of top-level comments, with the Q's and A's as child comments.

      Edit: Wow! I wasn't expecting this thread to have so much staying power! Love all the conversations that are being had. FYI The early posters including myself are still answering questions, so don't be shy!

      191 votes
    2. IAMA 3rd year Ph.D. student researching the cell biology of the Rice Blast fungus, Magnaporthe oryzae, and preparing for my candidacy qualifying exam. AMA.

      Hi Tilders! I am new here, but my experience with the community thus far has encouraged me to post an AMA. I've specifically decided to post this AMA in ~talk rather than ~science for more...

      Hi Tilders! I am new here, but my experience with the community thus far has encouraged me to post an AMA. I've specifically decided to post this AMA in ~talk rather than ~science for more exposure, and because I am hoping to field questions ranging from scientifically well-read to less-read, technical to curious, why care to who cares, and everything in between.

      I won't be posting "verifying proof", because like many of you, I love my anonymity here. However, I will include peer-reviewed citations to question answers when I feel it necessary. I will do my best to share free-access articles, but this won't always be possible. If I link an article of interest to you that is paid-access, message me; maybe, I may be able to get a copy to you. Also, please be patient for my replies. Even though it is summer where I am, I am still busy in the lab and thoughtful responses take time.

      Here is a brief background on the Rice Blast fungus to help get the conversation started:

      Rice is an important staple food consumed by nearly half of the global population Khush. 2005. From 10 - 30% of the annual rice harvest is lost to disease caused by Magnaporthe oryzae, which is enough rice to feed greater than 60 million people Skamnioti and Gurr. 2009. To cause infection, a three-celled asexual spore called a conidium attaches to the rice plant's leaves, stems, and even roots. Once attached, a germ tube emerges from one of the three cells and grows along the surface of the plant. Hydrophobic molecules on the plant surface, called hydrophobins, induce a developmental change in the growing germ tube. The growing germ tube tip begins to form a dome-shaped structure called the appressorium. This specialized structure swells and generates up to 80 Mpa of pressure, enough to penetrate kevlar. A penetration peg penetrates the plant cell tissue, and bulbous invasive hyphae colonize the plant cell tissue. The fungus keeps the invaded plant cell alive, while it consumes its nutrients, with the plant cell dying only when the invading growth moves to an adjacent cell Cruz-Mireles et al. 2021. Schematic.

      The Rice Blast research community focuses on all stages of its development. My work is focused on nuclear division during different developmental stages, and I am specifically working on understanding which and how motor proteins are involved in nuclear division in this fungus. Understanding the nuclear dynamics and the involved machinery will hopefully open avenues for controlling the plant infection and reducing the global crop loss.

      I hope you all find Rice Blast interesting, and I hope I will be able to answer many interesting questions!

      40 votes
    3. I've solo travelled ~3-4 weeks in the last twelve months - thoughts and AMA

      So in the last 12 months I've been to Japan, Reykjavik, Paris, and London by myself, and a couple of more countries with a friend (Brussels, Madrid, Seville, Paris^2, London^2, Reykjavik^2) and I...

      So in the last 12 months I've been to Japan, Reykjavik, Paris, and London by myself, and a couple of more countries with a friend (Brussels, Madrid, Seville, Paris^2, London^2, Reykjavik^2) and I just wanted to jot down some thoughts, tips, and maybe try to answer any questions that people might have about solo traveling.

      A full disclaimer, I'm an Asian guy who's relatively tall and broad in stature. The only reason I want to mention this is because I understand that non-masculine presenting people might have different experiences in general, especially when it comes to safety and perception. I'm not saying everywhere is dangerous nor that you should be afraid wherever you go, but I've never had to worry too much about walking alone at night nor being alone in a bar with only a couple of people. My other point of privilege is that I have a job that gives me a lot of PTO and requires me to take vacation even, which makes it easier for me to arrange these things.

      I started solo traveling this year, at the advice of my therapist. The one thing he mentioned a couple of times was that he noticed that his patients with anxiety seemed to make a lot of good progress while abroad by themselves, so I took his advice. My first "solo trip" was actually only 24 hours, in London. It was after a week-ish long trip that I last minute joined with a friend who was going to Spain on a work trip.

      My first kinda tip/observation comes here. If you're looking to try and spend some time solo tripping, a quick way to do it is that if you already have a trip planned with friends or family, you can always build in a "long layover" to somewhere along the way at the beginning or end of a group trip. I know that Iceland Air does this on their site for you, and Reykjavik is an amazing place with amazing people. I find myself sometimes sorting for 20+ hour layovers just for this.

      In London, I learned the biggest thing about traveling by myself that I really loved - that I could do anything, go anywhere, and not have to worry about the needs and wants of other people. Not that my travel companions are bad or not fun, but there's always something in the back of your mind of, "are these people enjoying it?" whereas by yourself you only need to worry about "am I enjoying it?" and that is a major relief.
      I find that I've been able to discover more about myself, the things I want to do and see. I didn't feel beholden to hit all the major tourist traps. In fact, I actually ended up in the Fashion and Textile museum. I've always loved fashion and thought that it would be more about that aspect of things, but when I went it was during an exhibit on quilting. The ticket seller looked at me funny and asked if I was sure I wanted to go into the exhibit, and I soon realized why, I was the youngest person there by a couple of decades, sticking out like a sore thumb. But honestly, it looked pretty interesting so I went through.

      I learned another thing that day, if you are interested and polite, people are generally very receptive to that. I walked through the exhibits, and it felt like at every quilt I stopped at, a British grandma would come up to me and ask me what my interest in quilting is, what I knew about it, and what I thought about the quilt. I knew absolutely 0 things about anything I was looking at, and they were all super happy to explain to me things about patterns, specific designs on each piece, why each piece was special, and so on. I learned a lot that day, and got to talk to a lot of grandmas and hear their stories and their interests. One was an engineer, who told me that the best engineers loved both arts and engineering, which still sticks with me now.

      My next trip was a couple of months later to Reykjavik and Paris. I booked a trip very last minute, within two weeks of the actual flight, iirc. But I figured if I was spending New Year's by myself at home, I might as well... not. I learned about the Iceland Air thing here, btw, effectively giving me two vacations in one. I spent New Years with a group of people I met on the plane, who graciously invited me to party with them, which was amazing.

      The thing I learned about my New Year in Iceland is that even though I was there for myself, doing the things that I wanted to do, it was okay to say yes sometimes to things that make you uncomfortable. I'm an introvert in general, with a lot of anxiety about pleasing people and making sure other people are happy. I'm sure others can relate. But being able to spend New Years with a group of people that I have met that same day was incredible because I realized that, yes, these people liked me, and yes, these people I probably will never see again, which lets me truly, honestly be myself without putting up a front because at the end of the day, if they knew who I was and they didn't like me, it's not like I'll ever have to deal with them again. Luckily, I'm still in contact with a couple of them and would love to visit them in the future, but your mileage may vary haha.

      In Paris, I learned that it was okay to cancel plans and lay in your hotel room even though there are things you wanted to do. I got a bit sick from partying too hard in Iceland, so I ended up staying in for a night and then some, missing a tour I booked at the Paris Catacombs (which I still haven't gone to even after going back to Paris a second time later in the year), but honestly it was very relaxing. As someone who likes to plan a bit before I leave, missing out on reservations made me learn that I didn't have to stick to the script all the time, it was okay and I'll still be okay. It wasn't the end of the world, though I was out a couple of dollars (I recognize this privilege though, so if you're tight on money please don't listen to me here), but I was getting healthy and happy and didn't need to push myself to do everything, something that I had to unlearn from my prior experiences with travel.

      That brings me to Japan, which I just came back from yesterday. I spent 10 days there and chatted and drank with locals, spent time by myself in an onsen (completely naked with a bunch of strangers btw), and got a new tattoo! I'm not sure if I learned anything too specific just yet, though I'll probably need to sit and think about it for a bit. But maybe the lesson might be that I don't have to take a lesson from everywhere I went.

      With alllll that being said, I'd love to answer any questions people might have, encourage people who might want to go solo traveling at least once, and give a place for other people to share their experience as well!

      39 votes
    4. I have severe and persistent mental illness. I now work as a public mental health professional. Ask me anything.

      Symptoms from my diagnoses of bipolar 2 and social anxiety disorder kept me from working, socializing, forming relationships, and living independently for more than a decade. I worked my ass off...

      Symptoms from my diagnoses of bipolar 2 and social anxiety disorder kept me from working, socializing, forming relationships, and living independently for more than a decade.

      I worked my ass off to improve my wellness, and for the past 6 years I have worked as a Peer Support Specialist for 2 different public agencies. I tell my story to other people with mental health and substance issues as part of my work. If anyone’s interested, I’d love to share it here too.

      41 votes
    5. Astronomer here! AMA!

      I'm here on the invitation of someone else, and not sure what this new website is all about yet/ the space stuff seems pretty scant, so anyone got a question about space they need answering? For...

      I'm here on the invitation of someone else, and not sure what this new website is all about yet/ the space stuff seems pretty scant, so anyone got a question about space they need answering?

      For those who don't know me from the certain other website, I am a radio astronomer currently at the Center for Astrophysics | Harvard & Smithsonian. Known under this user account on a certain other website for comments that begin with "astronomer here!"

      122 votes
    6. General surgery resident in the US on a 28 hour shift. AMA!

      Hi everyone! I am new to Tildes and wanted to say hi to the ~Health community. I am on a 28 hour emergency general surgery call today and have a bit of downtime. I also noticed that the post on...

      Hi everyone! I am new to Tildes and wanted to say hi to the ~Health community. I am on a 28 hour emergency general surgery call today and have a bit of downtime. I also noticed that the post on the moral crisis of America's doctors had some interest so I thought I would answer any questions about that or training to be a surgeon in the United States. I am finishing my 2nd year of a 7-year training program. Ask me (almost) anything!

      44 votes
    7. I am a cosmologist, AMA

      Ok ok disclaimer, I am a cosmology PhD candidate, don’t have the degree yet. However I do feel comfortable at this point calling myself a cosmologist (I think for the first time ever). In any...

      Ok ok disclaimer, I am a cosmology PhD candidate, don’t have the degree yet. However I do feel comfortable at this point calling myself a cosmologist (I think for the first time ever). In any case, with all the new people here, I think an AMA might be fun. I will try my best to answer all of the questions I get asked, but it may not happen quickly!

      A bit about my research. I study the conditions in the early universe, specifically when the cosmic microwave background was forming, and I use CMB data to test our understanding of this era. The CMB formed roughly 300,000 years after the big bang, when the universe was 1/1000th its current size. The patterns that we see in the temperature fluctuations of the CMB can tell us a lot about the universe at this early time, and specifically we can try to use them to see if anything ‘unexpected’ happened at this time, like a hitherto undiscovered particle annihilating into ‘normal’ particles (for example).

      Ask me anything about the early universe, or physics writ large, and I will do my best to answer!

      51 votes
    8. I've been on the hair loss drug Dutasteride for two years now. AMA.

      I'll start this post off by summarizing my hair loss experience. When I was 18, a few months shy of 19, I went to the barber and there was a miscommunication and the barber ended up buzzing my...

      I'll start this post off by summarizing my hair loss experience.

      When I was 18, a few months shy of 19, I went to the barber and there was a miscommunication and the barber ended up buzzing my hair off. This is the first time that I was able to see my hairline in a while and I saw that it was higher than I remembered. I was scared at first, I couldn't believe that my hairline was receding. But then I read a few things figures maybe it was just maturing, and then I eventually forgot. Actually a few months later I was back thinking to whether I was losing my hair or not. I talked to a cousin of mine and he said something about a pill that he was taking but that it had a possible side effect of erectile dysfunction. I wasn't going to take a chance on that when I wasn't even sure if I was actually balding.

      The next year and a half, I stop thinking about hair loss. It's like I had my memory wiped of that moment, probably due to stress from school. The only thing that happened is that I thought to myself was "man my hair is kind of weird right now." And also I had developed a scalp issue, which I later found out was psoriasis also due to stress.

      So, right before the pandemic hits in February 2020, me and my dad go have lunch at this restaurant. I take a shower and go out. My hair is still wet by the time we go to the restaurant. My dad looks up at my hair and asks "are you losing your hair?" And that's when I realized that I was indeed going bald. For the next three months, I was going through all the stages of grief. I was wildly depressed and anxious. I did some research into possible treatments. It took me a while to learn (or re-learn) about the pill known as finasteride. I then find out about a website where you can buy prescription meds without a prescription shipped over from India so I buy finasteride from there and I started treatment on May 1st 2020. I was 20 years old. I then go to the dermatologist two months later and they prescribe me Dutasteride which I have been on ever since.

      My initial side effect on the drug was watery semen, which cleared up a few weeks after starting the drug. My hair has re-grown a lot. It's back to it's original thickness, and my hairline has made a rather substantial comeback. It's not all back, but enough to the point where the average person wouldn't know I'm balding anymore.

      Let me know if you have any questions. I would love to post pictures, but I rather not if that's okay with everyone.

      18 votes
    9. IAmA chemical engineer who works with spent nuclear fuel. AMA!

      Thanks to @suspended and @deimos for the suggestion! Hey y’all, I am a basin chemistry engineer for the Department of Energy’s Savannah River Site in South Carolina. Our facility stores spent...

      Thanks to @suspended and @deimos for the suggestion!

      Hey y’all, I am a basin chemistry engineer for the Department of Energy’s Savannah River Site in South Carolina. Our facility stores spent nuclear fuel from a variety of research and experimental reactors underwater. Our specialty is highly-enriched aluminum-clad fuel, but we have a diverse array of unusual fuels from around the world. A good overview of fuel types can be found here.

      My primary responsibility is ensuring the basin water is kept highly pure to minimize corrosion to the fuel, as well as ensure it is free of radionuclides to the extent practicable. I’m happy to answer any questions I can about nuclear fuel, nuclear power, radioactive waste, etc.

      More links:
      Corrosion of Al-clad fuel
      Basin overview

      35 votes
    10. I am a Mozilla employee, AMAA

      Hi everybody, happy Friday! I am Aaron Klotz, a Staff Software Engineer on the GeckoView team at Mozilla Corporation. I have worked at Mozilla since the fall of 2012 and have worked on three...

      Hi everybody, happy Friday! I am Aaron Klotz, a Staff Software Engineer on the GeckoView team at Mozilla Corporation.

      I have worked at Mozilla since the fall of 2012 and have worked on three different teams across that time: Performance, Platform Integration & Security Hardening, and finally GeckoView.

      Given the recent news about layoffs, I thought it might be cathartic to do an AMA to share my experiences at Mozilla and try to set the record straight the best that I can. I would not dare try this in other forums, but since the Tildes community is capable of civil discussion, I'll do it here! I provided some proof a long time ago when I first joined Tildes, and I'd like to think that many people in this community are willing to vouch for me at this point, but if you want more, I can add it.

      Obviously I cannot discuss issues that are covered by my NDA (but fortunately most issues are not covered), and some details I might want to avoid out of sensitivity for people who were laid off. AMAA!

      EDIT 1: Also to make clear (if it wasn't obvious): These opinions are mine and mine alone, do not reflect the opinion of any Mozilla entity, etc. etc.

      EDIT 2: I'm logging off for the night, but I'll try to follow up throughout the weekend if I have time. Thanks for all the questions! Hopefully I've cleared up some things for you!

      EDIT 3: Okay, I think I've gone through the other questions asked over the weekend, but I'm going to stop now! Thanks for your interest! Now, I've got a mobile browser to help build!

      98 votes
    11. Ask a cosmology PhD student (almost) anything!

      Hi all, I am a PhD student focusing in cosmology. I wanted to up the science content here on Tildes, and I thought that one way to do so is to have an informal little Q&A session. As such, feel...

      Hi all,

      I am a PhD student focusing in cosmology. I wanted to up the science content here on Tildes, and I thought that one way to do so is to have an informal little Q&A session. As such, feel free to use this post to ask any questions you might have about cosmology specifically, and physics in general.

      This may not be as exciting as some other science AMAs given that I am a rather early graduate student, so there may be a lot of questions I don't know the answer to. However, I'm willing to try my best and answer over the next few days, and to let you know I don't know if I don't!

      A bit about myself: I did my undergraduate degree at the University of Chicago where I studied physics and mathematics, and then I was a student researcher in a computational cosmology group at a national lab. I subsequently enrolled at UC Davis to continue studying cosmology. Ask me anything about physics, cosmology, or high performance computing!

      I also invite anyone else with expertise to chime in as well!

      23 votes
    12. Turkey information thread: AmA you're curious about Turkey

      @gergir mentioned the idea, and I thought, why not give it a try? I'm a young adult from Turkey, lived up until now in Istanbul. Whether specific to that city or not, and whether about life,...

      @gergir mentioned the idea, and I thought, why not give it a try?

      I'm a young adult from Turkey, lived up until now in Istanbul. Whether specific to that city or not, and whether about life, tourist attractions, politics, culture, etc., just AmA.

      If you have anything you don't want to publicly ask, I'l love to help if you PM me your question.

      32 votes
    13. Anyone interested in learning a bit more about the Catalan situation? AMA

      Hey all, I'm Catalan (expat) and many of my friends in the USA or other countries in Europe tend to ask me a lot about the Catalan situation: independence, Puigdemont's extradition, political...

      Hey all,

      I'm Catalan (expat) and many of my friends in the USA or other countries in Europe tend to ask me a lot about the Catalan situation: independence, Puigdemont's extradition, political prisoners, police brutality, etc. I figured maybe some users here will be interested too?

      I consider myself equidistant to both the independentist nationalist, and the centralist nationalist movements (I'm more anti-borders than pro-borders, and I don't recognize the authority of any state), so I figure many of my responses will annoy everybody in Spain equally :-) . That said I would appreciate it if we all keep the discussion civil and as soon as I see flame wars I will stop answering questions.

      To my fellow Spaniards/Catalans. Feel free to chime in, contradict me with facts and opinions (I will probably not argue with you, I'm actually eager to learn more about other points of view in this matter), answer questions that I haven't answered for lack of knowledge, etc. Hell even if you are not from Spain but you know about it feel free to give me your two cents.

      Hope we get interesting discussions and we all learn from this!

      16 votes
    14. I am a bookkeeper and small business consultant, AMA

      My background: I've run a small bookkeeping business in California for the past 6 years, and worked as a bookkeeper for another 6 years before that. Over the years I've been deep in the books of...

      My background: I've run a small bookkeeping business in California for the past 6 years, and worked as a bookkeeper for another 6 years before that. Over the years I've been deep in the books of dozens of businesses, both successful and not. In the process of working closely with the owners of said businesses, I've learned a lot about what makes a small business work and what means I shouldn't get too attached. I'm a generalist, working with for and non-profit businesses as well as well to do individuals (who often have financial lives more complex than my business clients.)

      I'm bored and it's a smoky Sunday trapping me indoors, so if you have a question about bookkeeping or running/starting a small business, fire away.

      16 votes
    15. I'm Brian. I'm an intellectual property attorney and I moderate some stuff on Reddit, like IAmA. Ask Me Anything.

      Hey! I practice IP law with my brothers in Southern California. I primarily do trademark, copyright and litigation work. My brothers do patents and litigation. I also moderate stuff on Reddit,...

      Hey! I practice IP law with my brothers in Southern California. I primarily do trademark, copyright and litigation work. My brothers do patents and litigation.

      I also moderate stuff on Reddit, like IAmA. Ideally, I'd like to host some AMAs here. This is kind of a test to see how it goes at an early stage.

      Ask me stuff!

      Proof with TruePic

      Edit: This was fun. Thank you guys. I'm headed out for a bit. :)

      22 votes