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21 votes
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How Portugal decriminalized drugs
8 votes -
First over-the-counter birth control pill gets US FDA approval
58 votes -
Johnson & Johnson has granted Stop TB Partnership license to produce generic bedaquiline in low and middle-income countries
33 votes -
An open letter to Johnson & Johnson regarding its strategy to extend its patent on bedaquiline leading to a predicted six million lives lost over four years
79 votes -
Most patients using weight-loss drugs like Wegovy stop within a year, data show
10 votes -
Australia legalises psychedelics for mental health
29 votes -
Could this drug help cure PTSD? With Rachel Nuwer - Factually
8 votes -
There’s finally a psychedelic caucus in congress — here’s what they’re doing
21 votes -
Heat sensitivity/intolerance
So it is 80 degrees fahrenheit here today which usually would not be an issue for me but today I was too hot and sweaty. I am perimenopausal (49 years old) and I knew that could mess with heat...
So it is 80 degrees fahrenheit here today which usually would not be an issue for me but today I was too hot and sweaty. I am perimenopausal (49 years old) and I knew that could mess with heat tolerance. What I had not realized until today is that heat intolerance is also a side effect of many blood pressure medicines, antidepressants and allergy meds. And I am on all of those now.
I have just ordered some gadget that is a fan that goes around my neck and can be recharged via USB which seemed worth trying. And of course I will drink plenty of water, and try to stay in air conditioning whenever I can. Any other advice on how to deal with increased sensitivity to heat / higher heat intolerance? It is still early enough in the summer that the worst summer heat here is yet to come, so having some more tips might help me. Thanks!
26 votes -
Goodbye, Ozempic
33 votes -
How do you keep track of your medication refills?
Every person in my household takes a daily regimen of prescription medication and/or supplements. We keep ending up in situations where we run out of something because we don’t have a good way to...
Every person in my household takes a daily regimen of prescription medication and/or supplements. We keep ending up in situations where we run out of something because we don’t have a good way to keep track of our remaining supply of each thing. We need a better system for managing this!
We each use a 28-day (4 week) pill dispenser box which helps somewhat. I refill the dispensers when they are empty. The problem is, some of the medications run out in the last week of the dispenser. At the time I fill it, it’s way too early to call the pharmacy for a refill. But by the time the supply runs out I’ve forgotten about it and have to scramble to get more. I hope I’m explaining that clearly. It’s complicated because every medication runs out on a different schedule.
If you’ve got a solution to this problem please share it!
15 votes -
How a dose of MDMA transformed a white supremacist
27 votes -
US medical insurers clamping down on doctors who prescribe Ozempic for weight loss
22 votes -
Lung cancer pill cuts risk of death by half, says ‘thrilling’ study
11 votes -
Abortion pills: An option not talked about
6 votes -
Bioluminescence helps researchers develop cancer drugs for brain
3 votes -
Finland is the European country with the highest proportion of under 25s dying from drugs
6 votes -
Are cures for some of the world’s deadliest diseases hiding in our sewers?
7 votes -
Inside Denmark's opioid crisis – more teens are abusing opioids because they take the pills both to get high and to cope with anxiety
3 votes -
The ‘breakthrough’ obesity drugs that have stunned researchers
17 votes -
UK girl with deadly inherited condition is cured with gene therapy on NHS
9 votes -
Semaglutide weight loss injections to be made available directly from pharmacies in the UK
6 votes -
British Columbia embarks on bold experiment to decriminalize hard drugs - Possession of small amounts of fentanyl, heroin, cocaine and other hard drugs will be allowed in Canada’s westernmost province
10 votes -
Cancer mRNA vaccine completes pivotal trial
5 votes -
Millions of Alzheimer’s patients have been given hope after a new drug has been shown to slow memory decline by 27% over eighteen months. It's the biggest breakthrough in a generation.
8 votes -
FDA approves most expensive drug ever, a $3.5 million-per-dose gene therapy for hemophilia B
6 votes -
The Ice Bucket Challenge wasn't just for social media. It helped fund a new ALS drug.
6 votes -
How testosterone therapy is transforming aging
5 votes -
Thailand to give away one million free cannabis plants to households, minister says
10 votes -
Nootropics and scams - Exposing fake reviews with Python
12 votes -
Sacklers raise their offer to settle opioid lawsuits by more than $1 billion
7 votes -
How to know if you’re addicted
8 votes -
More young kids are getting sick from cannabis edibles
7 votes -
The new meth: Different chemically than it was a decade ago, the drug is creating a wave of severe mental illness and worsening America’s homelessness problem
22 votes -
A major reversal on aspirin highlights a concept everyone should understand
12 votes -
Merck says research shows its COVID-19 pill works against variants
13 votes -
The Sacklers, who made billions from OxyContin, win immunity from US opioid lawsuits
10 votes -
Thoughts on SSRIs?
Hello everyone, I recently got put on some SSRI for my worsening suicidal ideation and honestly I can't believe the difference it's made. It's like a version of myself that I find hard to believe...
Hello everyone,
I recently got put on some SSRI for my worsening suicidal ideation and honestly I can't believe the difference it's made. It's like a version of myself that I find hard to believe existed, but can draw parallels with the version of me before I got depressed, etc.
I'm just curious how I should be viewing these changes in me: Are they really me without depression/anxiety or is it a more lurid exaggerated version of that?
Any other thoughts on SSRIs in general welcome! I'm interested in seeing Tildians' thoughts on them :)
18 votes -
The invisible addiction: Caffeine makes us more energetic, efficient and faster. But we have become so dependent that we need it just to get to our baseline.
25 votes -
California bill to decriminalize psychedelics is approved by Senate, now moves on to Assembly
26 votes -
Medication for depression
Hello my lovelies, I struggle with a moderate amount of anxiety and obsession with self-image, which tend to amalgamate as some kind of depression or other over time. At least I think they do....
Hello my lovelies,
I struggle with a moderate amount of anxiety and obsession with self-image, which tend to amalgamate as some kind of depression or other over time. At least I think they do. I've never really been sure if what I experience is actually depression, or if I'm just a Mopey Idiot, or if I have a more acute cognitive issue that I'm not aware of.
I keep very precise semi-quantitative logs of my mood and behavior every day, and they suggest to me that some of my stress is related to being a little overloaded. I'm working on cutting back on some of that responsibility. But it's also extremely obvious to me that, for quite some time—I think since about early October 2019—I've lacked the physical energy that typically allows me to be consistently happy. There was no one, singular "proximate cause" two years ago, certainly it was none of my actual obligations (at that time I had very little work to speak of). However, I nevertheless very distinctly remember that my energy was suddenly just sapped, and has not come back to the level it was at before. The best theory I have is that it might've been a mini-existential crisis triggered immediately by some books I'd been reading, with a background of relatively more social isolation than usual. There have been specific circumstances since then in which I can be high-energy (and I mean be, not just act like I am), but they are fleeting and rare. The overall background energy of my life has been different.
In short, I do not really have a solid anchor per se, even as I have many little mini-anchors. I have been floating around for a while as a result.
At least that has been my working theory for a little while. The persistence of my condition has led me to question whether that theory is useful, or whether there is something fundamentally wrong with my brain. I am Young and Naive so I simply do not know how to tell. The pandemic has made it much more challenging to figure out the root cause of my problems, because I cannot tell if they are just because I can't do the fun activities I like doing in the social environments I like doing them in, or something presumably biochemical.
Things that each help a little:
- Getting more sleep
- Getting more exercise
- Being good about meditating, or when my therapist is useful (rarely)
- Being successful (I have a job for the summer and a likely career after I graduate. Knock on wood)
- Being hot as fuck (I'm not that attractive, but I feel pretty after I exercise, or when I dress nice, or when people compliment my body)
Things that each help a lot:
- Having extremely attentive and caring friends
- Not being around people who constantly drain me
- Consuming certain substances
Specifically, the most non-low-energy I've felt in a long time was when I ate some funky little mushrooms with my friend this year. Specifically, after I snapped back to reality (mom's spaghetti). I was just more alert and more able to function properly. My brain operated at its normal capacity; words flowed freely from my mouth in a gorgeous array of sentences; positive banter was at an all-time high; I was positive and optimistic; and so on. You know how you can sort of visualize the ideas popping around and the gears turning when you're sober but just really on top of your social life? Well that's what it was. Unfortunately my ability to be a normal person only lasted like 1 or 2 days from there, and then it was back to the same old.
This has made me ask the question: might it be prudent to look into some sort of legal medical prescription that would have a similar effect? That is, anti-depressants or like whatever. I'm also open to alternative treatments but I am mainly asking about prescription meds. I just don't know anything about the whole world of medication. I almost never take meds for anything ever, even physical injuries, and I'm afraid that if I start doing medication I'll never be able to stop. The concept of always being medicated is a little scary to me. Like even if it helps, I'm still worried. But I kind of feel like nothing I've done so far has been able to permanently work, so I kind of need to do something.
I appreciate any thoughts that you can give!!!
xoxoxo
beezselzak18 votes -
MDMA-assisted therapy for severe PTSD: A randomized, double-blind, placebo-controlled phase 3 study
10 votes -
Cost Plus Drug Company: Low cost versions of high cost generic drugs
4 votes -
Oregon legalizes psilocybin mushrooms (for therapeutic purposes) and decriminalizes all drugs
32 votes -
Eli Lilly says its monoclonal antibody cocktail is effective in treating Covid-19
7 votes -
Sweden has the highest proportion of drug-related deaths in the European Union, with eighty-one cases per one million citizens – nearly four times higher than the EU average
11 votes -
The "date-rape drug" narrative has been weaponized against recreational GHB users
6 votes -
Four terminally ill Canadians get special exemption to use psychedelic therapy
5 votes -
"Knowing it could kill you isn’t a deterrent": The deadly trade in diet pills
6 votes