Good Work piece from two weeks ago or so on this very subject. Once again, comedy news spoofs beat the mainstream guys to the punch (or are newsrooms just skimming ideas from the funny folks?).
Good Work piece from two weeks ago or so on this very subject. Once again, comedy news spoofs beat the mainstream guys to the punch (or are newsrooms just skimming ideas from the funny folks?).
I don't think this means investigative journalism itself is dead, but rather that it's coming from different places that tend not to be major news agencies anymore.
I don't think this means investigative journalism itself is dead, but rather that it's coming from different places that tend not to be major news agencies anymore.
It's not dead. It's just your sources of information. After I've started to use RSS more often, I'm getting more investigative journalism. I'm not tied anymore to what people usually upvote/share...
It's not dead. It's just your sources of information. After I've started to use RSS more often, I'm getting more investigative journalism. I'm not tied anymore to what people usually upvote/share - which is almost always some bland mainstream media.
I actually only learned this because I randomly watched this video after not touching youtube for months, and then did a quick google search to figure out whether it's actually true. And decided...
I actually only learned this because I randomly watched this video after not touching youtube for months, and then did a quick google search to figure out whether it's actually true. And decided to post a text source so nobody has to sit through the video
This randomized, double-blind, placebo-controlled Phase 2 study evaluates whether pentadecapeptide BPC 157 (BPC-157), an investigational peptide, can speed structural healing and functional recovery after an acute grade II hamstring muscle strain. Participants will receive BPC 157 or placebo for 14 days in addition to a standardized rehabilitation program. The co-primary endpoints are time to return to unrestricted sport and change in MRI-assessed injury volume at Day 14.
Well, that's terrifying. Depending on the type of cancer, the later stages are a lot less treatable compared to early stages. Some are already very aggressive, and it can be easy to write off...
Because these proteins are associated with tissue growth, there is a risk that if you’ve got an early-stage cancer developing that you didn’t know about, peptides could accelerate its advancement, he says.
Well, that's terrifying. Depending on the type of cancer, the later stages are a lot less treatable compared to early stages. Some are already very aggressive, and it can be easy to write off early symptoms.
I’m am kind of glad that I never made it into Silicon Valley. I hear so many stories about people taking crazy drugs and diets there that I wonder what kind of stressful lives these people live to...
I’m am kind of glad that I never made it into Silicon Valley. I hear so many stories about people taking crazy drugs and diets there that I wonder what kind of stressful lives these people live to pressure them into these risky behaviors.
It’s really exaggerated. We’re talking a tiny fraction of the population actually doing this stuff. It’s also conflating Silicon Valley and San Francisco. You’ll find more of these experimental...
It’s really exaggerated. We’re talking a tiny fraction of the population actually doing this stuff.
It’s also conflating Silicon Valley and San Francisco. You’ll find more of these experimental types in SF. SV is just a bunch of extremely boring, extremely expensive suburb. It’s just full of 30-50 year old people working day jobs in a sea of single family homes with shitty traffic. People going in expecting it to be some kind of sci fi utopia or dystopia will be disappointed to find out it’s just a normal American suburb dystopia, just that the average family income is over $200k.
I feel like it’s fair to say at this point that the term “Silicon Valley” is less about the geographic origin of the name and more about the tech scene in the Bay Area. I regularly hear people use...
I feel like it’s fair to say at this point that the term “Silicon Valley” is less about the geographic origin of the name and more about the tech scene in the Bay Area. I regularly hear people use the term to include SF even though yes traditionally SV is the South Bay
Regarding experimentation, SF does have an interesting drug scene. My understanding is all natural psychedelics are decriminalized. So there are a ton of nice brick and mortar stores selling...
Regarding experimentation, SF does have an interesting drug scene. My understanding is all natural psychedelics are decriminalized. So there are a ton of nice brick and mortar stores selling psychedelic cacti powder, magic mushrooms, DMT vapes, and more. I also just learned about a place selling 99% pure mescaline which can be hard to find even on the dark web.
I really like it here. Honestly I don’t relate to the unhappy or stressed out tech workers. When I first moved to SF I would look at the people in my expensive apartment building - people that are...
I really like it here. Honestly I don’t relate to the unhappy or stressed out tech workers. When I first moved to SF I would look at the people in my expensive apartment building - people that are probably making $300k or more and don’t have kids - and I saw a lot of burn out in their eyes. These are people with bank account balances most people would call “life changing money” and they aren’t choosing to change their lives? I guess they don’t consider their options.
But you gotta save up to buy an overpriced house. I hear once you own property that’s when you’re allowed to be happy /s
I can’t speak for all of Silicon Valley, but the pressure of aging is pretty rough. Especially when competing against all these young kids who keep getting stronger and faster while I get slower...
I can’t speak for all of Silicon Valley, but the pressure of aging is pretty rough. Especially when competing against all these young kids who keep getting stronger and faster while I get slower and more broken.
These crazy diets and drugs are more limited to San Francisco itself rather than the Silicon Valley some 40-50 miles south as @stu2b50 points out. Even within San Francisco, the craziness is more...
These crazy diets and drugs are more limited to San Francisco itself rather than the Silicon Valley some 40-50 miles south as @stu2b50 points out. Even within San Francisco, the craziness is more limited to a small subset of crazy tech workers. I also don't think it's entirely work pressure that's pushing people to these diets, rather than the desire to be on the cutting edge. I think with this latest AI startup wave, people have a desire to be the next big thing and be on the cutting edge so they'll do anything to uphold that image.
The grand appeal of peptides is they feel like damn near only drugs that work in real time. We all know about glp1s and weight loss, but for example there is one to get a noticeable tan in just...
The grand appeal of peptides is they feel like damn near only drugs that work in real time.
We all know about glp1s and weight loss, but for example there is one to get a noticeable tan in just one day in the sun (even Fitzpatrick type skin can tan!), or there is one to sharply increase libido & orgasm strength for the day (for women!!), one to speed up healing injuries, the range is incredible.
I have mixed feelings about articles like this though, I feel like the unintended consequence is it will lead more lay people to seek out the grey market which will cause people to get hurt which generally leads to stricter regulation.
I’m not sure if US is going either make a lot of these peptides illegal or if they will get picked up by pharmaceutical companies and become prohibitively expensive. Either way access will be restricted.
I’m saying all this selfishly as a grey market user myself…I wish that it could still be like an obscure club. As this club gets bigger it becomes more common for new people in the community to offer others dangerous advice while not fully grasping the scope of risks they are taking themselves.
It's not clear to me why pharmaceutical companies "picking up" peptides would make them prohibitively expensive. Getting GLP-1 through the grey market via compounding pharmacies is generally more...
It's not clear to me why pharmaceutical companies "picking up" peptides would make them prohibitively expensive. Getting GLP-1 through the grey market via compounding pharmacies is generally more expensive than getting a mainstream pharmaceutical formulation with a doctor's prescription, isn't it? It's certainly much more dangerous, but I assume as someone already using grey market peptides you're appraised of the risks you're taking on that front.
I don’t consider the compounding pharmacies grey market. Those are by prescription and yes, very expensive because it’s usually telehealth providers that don’t accept insurance and also charge a...
I don’t consider the compounding pharmacies grey market. Those are by prescription and yes, very expensive because it’s usually telehealth providers that don’t accept insurance and also charge a visit fee on top of the medication. Or they’re used by medspas that really crank the price up. If you can get your pcp or other established doctor to prescribe it and your insurance will cover it, I believe you can get it much cheaper- but insurance companies don’t want to pay for it unless you meet very specific criteria. Although, I’m not sure how the introduction of oral semaglutide has changed things.
By grey market I’m talking about vendors shipping to you from china and you reconstitute it yourself lol. It is very risky, but there is some harm reduction steps to take. I make sure my source has third party testing for each lot for example. (pls no one DM me asking for sources, I will not reply)
My partially non-serious hot take is to just let people do whatever they want to themselves and let them hash it out with Darwin. I'll be over here NOT doing things to myself I don't fully understand.
My partially non-serious hot take is to just let people do whatever they want to themselves and let them hash it out with Darwin.
I'll be over here NOT doing things to myself I don't fully understand.
I don't mean to be an asshole, and I know where you're coming from, but everything we do is not fully understood. At some level, we have questions about everything.
I don't mean to be an asshole, and I know where you're coming from, but everything we do is not fully understood. At some level, we have questions about everything.
I mean if you want to get philosophical and abstract about it, sure. But people build their entire lives around understanding these kinds of things as much as possible. There are tons of resources...
I mean if you want to get philosophical and abstract about it, sure.
But people build their entire lives around understanding these kinds of things as much as possible. There are tons of resources today for a person to learn about these things themselves.
And by understand, I don't mean "know everything there is to know" but understand the mechanisms that makes something like that work and the basics of the biology and science, to be able to know when someone's bullshitting you.
Like I don't need to know everything there is to know about viruses to know that drinking bleach won't kill COVID, I just need to understand enough about how viruses, the human body, and chemicals work to be able to call bullshit.
When you don't understand how anything works, or in the case of most people they don't CARE how anything works, it leaves you vulnerable to falling for bullshit that can harm you.
Like I know enough about how computers work that a scammer calling me about a virus on my computer's not going to work. I know enough about virology to know that drinking bleach, sticking a UV sanitizer down my throat, or taking an antiparasitic horse medication isn't going to work.
Sure. Peptides are in an intermediate zone between double blind placebo controlled studies and drinking bleach though. In most cases we have some idea what the biological mechanism is, and...
Sure. Peptides are in an intermediate zone between double blind placebo controlled studies and drinking bleach though. In most cases we have some idea what the biological mechanism is, and probably animal studies.
Good Work piece from two weeks ago or so on this very subject. Once again, comedy news spoofs beat the mainstream guys to the punch (or are newsrooms just skimming ideas from the funny folks?).
Honestly I think that investigative journalism is mostly dead at this point. I can’t remember any stories this year that broke from a news agency.
ProPublica is still around so it’s not completely dead, just sort of dead-ish?
Fair. I haven’t paid much attention to them for a while for some reason.
I don't think this means investigative journalism itself is dead, but rather that it's coming from different places that tend not to be major news agencies anymore.
I feel like 404 media is starting to turn into clickbait but it had a good run for a bit. I guess they are facing some economic pressures.
It's not dead. It's just your sources of information. After I've started to use RSS more often, I'm getting more investigative journalism. I'm not tied anymore to what people usually upvote/share - which is almost always some bland mainstream media.
I actually only learned this because I randomly watched this video after not touching youtube for months, and then did a quick google search to figure out whether it's actually true. And decided to post a text source so nobody has to sit through the video
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We will get a bit of evidence regarding BPC-157 soon at least.
https://clinicaltrials.gov/study/NCT07437547
Well, that's terrifying. Depending on the type of cancer, the later stages are a lot less treatable compared to early stages. Some are already very aggressive, and it can be easy to write off early symptoms.
People are so ignorant and peptide-pilled in SF that I recommended my friend take creatine and someone nearby asked if that was a peptide.
I’m am kind of glad that I never made it into Silicon Valley. I hear so many stories about people taking crazy drugs and diets there that I wonder what kind of stressful lives these people live to pressure them into these risky behaviors.
It’s really exaggerated. We’re talking a tiny fraction of the population actually doing this stuff.
It’s also conflating Silicon Valley and San Francisco. You’ll find more of these experimental types in SF. SV is just a bunch of extremely boring, extremely expensive suburb. It’s just full of 30-50 year old people working day jobs in a sea of single family homes with shitty traffic. People going in expecting it to be some kind of sci fi utopia or dystopia will be disappointed to find out it’s just a normal American suburb dystopia, just that the average family income is over $200k.
I feel like it’s fair to say at this point that the term “Silicon Valley” is less about the geographic origin of the name and more about the tech scene in the Bay Area. I regularly hear people use the term to include SF even though yes traditionally SV is the South Bay
Regarding experimentation, SF does have an interesting drug scene. My understanding is all natural psychedelics are decriminalized. So there are a ton of nice brick and mortar stores selling psychedelic cacti powder, magic mushrooms, DMT vapes, and more. I also just learned about a place selling 99% pure mescaline which can be hard to find even on the dark web.
I really like it here. Honestly I don’t relate to the unhappy or stressed out tech workers. When I first moved to SF I would look at the people in my expensive apartment building - people that are probably making $300k or more and don’t have kids - and I saw a lot of burn out in their eyes. These are people with bank account balances most people would call “life changing money” and they aren’t choosing to change their lives? I guess they don’t consider their options.
But you gotta save up to buy an overpriced house. I hear once you own property that’s when you’re allowed to be happy /s
I can’t speak for all of Silicon Valley, but the pressure of aging is pretty rough. Especially when competing against all these young kids who keep getting stronger and faster while I get slower and more broken.
These crazy diets and drugs are more limited to San Francisco itself rather than the Silicon Valley some 40-50 miles south as @stu2b50 points out. Even within San Francisco, the craziness is more limited to a small subset of crazy tech workers. I also don't think it's entirely work pressure that's pushing people to these diets, rather than the desire to be on the cutting edge. I think with this latest AI startup wave, people have a desire to be the next big thing and be on the cutting edge so they'll do anything to uphold that image.
Kind of a symptom of looksmaxxxing/blackpill stuff going so mainstream
The grand appeal of peptides is they feel like damn near only drugs that work in real time.
We all know about glp1s and weight loss, but for example there is one to get a noticeable tan in just one day in the sun (even Fitzpatrick type skin can tan!), or there is one to sharply increase libido & orgasm strength for the day (for women!!), one to speed up healing injuries, the range is incredible.
I have mixed feelings about articles like this though, I feel like the unintended consequence is it will lead more lay people to seek out the grey market which will cause people to get hurt which generally leads to stricter regulation.
I’m not sure if US is going either make a lot of these peptides illegal or if they will get picked up by pharmaceutical companies and become prohibitively expensive. Either way access will be restricted.
I’m saying all this selfishly as a grey market user myself…I wish that it could still be like an obscure club. As this club gets bigger it becomes more common for new people in the community to offer others dangerous advice while not fully grasping the scope of risks they are taking themselves.
It's not clear to me why pharmaceutical companies "picking up" peptides would make them prohibitively expensive. Getting GLP-1 through the grey market via compounding pharmacies is generally more expensive than getting a mainstream pharmaceutical formulation with a doctor's prescription, isn't it? It's certainly much more dangerous, but I assume as someone already using grey market peptides you're appraised of the risks you're taking on that front.
I don’t consider the compounding pharmacies grey market. Those are by prescription and yes, very expensive because it’s usually telehealth providers that don’t accept insurance and also charge a visit fee on top of the medication. Or they’re used by medspas that really crank the price up. If you can get your pcp or other established doctor to prescribe it and your insurance will cover it, I believe you can get it much cheaper- but insurance companies don’t want to pay for it unless you meet very specific criteria. Although, I’m not sure how the introduction of oral semaglutide has changed things.
By grey market I’m talking about vendors shipping to you from china and you reconstitute it yourself lol. It is very risky, but there is some harm reduction steps to take. I make sure my source has third party testing for each lot for example. (pls no one DM me asking for sources, I will not reply)
Ah okay, the grey market you're referring to is more similar to grey market estrogen then, that makes sense.
My partially non-serious hot take is to just let people do whatever they want to themselves and let them hash it out with Darwin.
I'll be over here NOT doing things to myself I don't fully understand.
I don't mean to be an asshole, and I know where you're coming from, but everything we do is not fully understood. At some level, we have questions about everything.
I mean if you want to get philosophical and abstract about it, sure.
But people build their entire lives around understanding these kinds of things as much as possible. There are tons of resources today for a person to learn about these things themselves.
And by understand, I don't mean "know everything there is to know" but understand the mechanisms that makes something like that work and the basics of the biology and science, to be able to know when someone's bullshitting you.
Like I don't need to know everything there is to know about viruses to know that drinking bleach won't kill COVID, I just need to understand enough about how viruses, the human body, and chemicals work to be able to call bullshit.
When you don't understand how anything works, or in the case of most people they don't CARE how anything works, it leaves you vulnerable to falling for bullshit that can harm you.
Like I know enough about how computers work that a scammer calling me about a virus on my computer's not going to work. I know enough about virology to know that drinking bleach, sticking a UV sanitizer down my throat, or taking an antiparasitic horse medication isn't going to work.
Sure. Peptides are in an intermediate zone between double blind placebo controlled studies and drinking bleach though. In most cases we have some idea what the biological mechanism is, and probably animal studies.