When is is okay to give up on making a situation work?

I legitimately ask, as I’ve pretty much given up on most “immediate” family in recent months. As an American federal civilian employee, I found the rhetoric of my immediate family crazy enough to warrant cutting them out of my life. I can’t get beyond their clear contempt for my livelihood. Despite conversations regarding how a certain admin’s policies are making my life worse, I have been told constantly not to complain because it could be worse. So I have “given up” and no longer interact with them. There have been further conversations prior to this, but I don’t think it’s necessarily important to the conversation.

I ask this legitimately, as I am feeling guilt over it, despite the fact that I no longer feel dread or anxiety about it. I haven’t visited immediate family in over 2 months now, despite living within walking distance.

At what point should one continue making attempts to repair to maintain relationships, even familial, and when is it okay to end them?

Part 1: https://gimletmedia.com/shows/reply-all/llhd33/152-the-real-enemy-part-1

Part 2: https://gimletmedia.com/shows/reply-all/94hwe43/153-the-real-enemy-part-2

Part 3: https://gimletmedia.com/shows/reply-all/j4hl3vj/154-the-real-enemy-part-3