You might be able to tell by my username which is my favorite audio drama. If you haven't heard of it, Wolf 359 is a space opera dramedy focused on a cast of deeply likable characters who find themselves carrying out mysterious research onboard a space station owned by a soulless corporation. Heads up, the whole thing is very enjoyable but the creators say the real story doesn't get going for real until about episode 9 and I would agree. It's funny and entertaining but gets pretty serious around there. Don't worry, the early episodes are super short and still good.

Other audio dramas I highly recommend are:

Bronzetown
1865
Limetown
Edict Zero FIS
Station 151
Archive 81
The Magnus Archives
Theater of Tomorrow
The Hyacinth Disaster
Life After / The Message