Have you not heard of that madman who lit a lantern in the bright morning hours, ran to the marketplace, and cried incessantly: "I seek God! I seek God!" —As many of those who did not believe in God were standing around just then, he provoked much laughter. Has he got lost? asked one. Did he lose his way like a child? asked another. Or is he hiding? Is he afraid of us? Has he gone on a voyage? emigrated? —Thus they yelled and laughed.

The madman jumped into their midst and pierced them with his eyes. “Whither is God?" he cried; "I will tell you. We have killed him—you and I. All of us are his murderers. But how did we do this? How could we drink up the sea? Who gave us the sponge to wipe away the entire horizon? What were we doing when we unchained this earth from its sun? Whither is it moving now? Whither are we moving? Away from all suns? Are we not plunging continually? Backward, sideward, forward, in all directions? Is there still any up or down? Are we not straying as through an infinite nothing? Do we not feel the breath of empty space? Has it not become colder? Is not night continually closing in on us? Do we not need to light lanterns in the morning? Do we hear nothing as yet of the noise of the gravediggers who are burying God? Do we smell nothing as yet of the divine decomposition? Gods, too, decompose. God is dead. God remains dead. And we have killed him.”

"How shall we comfort ourselves, the murderers of all murderers? What was holiest and mightiest of all that the world has yet owned has bled to death under our knives: who will wipe this blood off us? What water is there for us to clean ourselves? What festivals of atonement, what sacred games shall we have to invent? Is not the greatness of this deed too great for us? Must we ourselves not become gods simply to appear worthy of it? There has never been a greater deed; and whoever is born after us—for the sake of this deed he will belong to a higher history than all history hitherto."

Here the madman fell silent and looked again at his listeners; and they, too, were silent and stared at him in astonishment. At last he threw his lantern on the ground, and it broke into pieces and went out. "I have come too early," he said then: "my time is not yet. This tremendous event is still on its way, still wandering; it has not yet reached the ears of men. Lightning and thunder require time; the light of the stars requires time; deeds, though done, still require time to be seen and heard. This deed is still more distant from them than the most distant stars—and yet they have done it themselves.

It has been related further that on the same day the madman forced his way into several churches and there struck up his requiem aeternam deo. Led out and called to account, he is said always to have replied nothing but: "What after all are these churches now if they are not the tombs and sepulchers of God?”

• Friedrich Nietzsche, “Gay Science”, 1882

The most merciful thing in the world, I think, is the inability of the human mind to correlate all its contents. We live on a placid island of ignorance in the midst of black seas of infinity, and it was not meant that we should voyage far. The sciences, each straining in its own direction, have hitherto harmed us little; but some day the piecing together of dissociated knowledge will open up such terrifying vistas of reality, and of our frightful position therein, that we shall either go mad from the revelation or flee from the deadly light into the peace and safety of a new dark age.

• Howard Phillips Lovecraft, “The Call of Cthulhu”, 1928

“Humans desired reasons. Reasons for pain. Reasons for sadness. Reasons for life. Reasons for death. Why were their lives filled with suffering? Why were their deaths absurd? They wanted reasons for the destiny that kept transcending their knowledge.”

“And that was God.”

• Kentaro Miura, “Berserk” (83), 1996

What's it say about life, hm? You gotta get together, tell yourself stories that violate every law of the universe just to get through the goddamn day.

• Nic Pizzolatto, “True Detective”, 2014

The universe of modern science engendered a profounder horror in Lovecraft’s writings than that stemming from its tremendous distances and its highly probably alien and powerful non-human inhabitants. For the chief reason that man fears the universe revealed by materialistic science is that it is a purposeless, soulless place. To quote Lovecraft’s “The Silver Key”, man can hardly bear the realization that “the blind cosmos grinds aimlessly on from nothing to something and from something back to nothing again, neither heeding nor knowing the wishes or existence of the minds that flicker for a second now and then in the darkness.”

• Fritz Leiber, “A Literary Copernicus”, 1949

With respect to the theological view of the question; this is always painful to me.— I am bewildered.— I had no intention to write atheistically. But I own that I cannot see, as plainly as others do, & as I should wish to do, evidence of design & beneficence on all sides of us. There seems to me too much misery in the world. I cannot persuade myself that a beneficent & omnipotent God would have designedly created the Ichneumonidæ with the express intention of their feeding within the living bodies of caterpillars, or that a cat should play with mice.

• Charles Darwin, in a letter to Asa Gray, 1860

In a way, Darwin discovered God—a God that failed to match the preconceptions of theology, and so passed unheralded. If Darwin had discovered that life was created by an intelligent agent—a bodiless mind that loves us, and will smite us with lightning if we dare say otherwise—people would have said "My gosh! That's God!"

But instead Darwin discovered a strange alien God—not comfortably "ineffable", but really genuinely different from us. Evolution is not a God, but if it were, it wouldn't be Jehovah. It would be H. P. Lovecraft's Azathoth, the blind idiot God burbling chaotically at the center of everything, surrounded by the thin monotonous piping of flutes.

Which you might have predicted, if you had really looked at Nature.

• Eliezer Yudkowsky, “An Alien God”, 2007

The whole earth, continually steeped in blood, is nothing but an immense altar on which every living thing must be sacrificed without end, without restraint, without respite until the consummation of the world, until the extinction of evil, until the death of death.

• Joseph de Maistre, “St. Petersburg Dialogues”, 1821

One night in times long since vanished, man awoke and saw himself. He saw that he was naked under the cosmos, homeless in his own body. Everything opened up before his searching thoughts, wonder upon wonder, terror upon terror, all blossomed in his mind.

Then woman awoke, too, and said that it was time to go out and kill something. And man took up his bow, fruit of the union between the soul and the hand, and went out under the stars. But when the animals came to their water-hole, where he out of habit waited for them, he no longer knew the spring of the tiger in his blood, but a great psalm to the brotherhood of suffering shared by all that lives.

That day he came home with empty hands, and when they found him again by the rising of the new moon, he sat dead by the waterhole.

• Peter Wessel Zapffe, “The Last Messiah”, 1933

For the rest of the earth’s organisms, existence is relatively uncomplicated. Their lives are about three things: survival, reproduction, death—and nothing else. But we know too much to content ourselves with surviving, reproducing, dying—and nothing else. We know we are alive and know we will die. We also know we will suffer during our lives before suffering—slowly or quickly—as we draw near to death. This is the knowledge we “enjoy” as the most intelligent organisms to gush from the womb of nature. And being so, we feel shortchanged if there is nothing else for us than to survive, reproduce, and die. We want there to be more to it than that, or to think there is. This is the tragedy: Consciousness has forced us into the paradoxical position of striving to be unself-conscious of what we are—hunks of spoiling flesh on disintegrating bones.

• Thomas Ligotti, “The Conspiracy Against the Human Race”, 2010

This realization threatens to put us in a persistent state of existential fear.

• Sheldon Solomon, Jeff Greenberg, Tom Pyszczynski, “The Worm at the Core: On the Role of Death in Life”, 2015

What does it mean to be a self-conscious animal? The idea is ludicrous, if it is not monstrous. It means to know that one is food for worms. This is the terror: to have emerged from nothing, to have a name, consiousness of self, deep inner feelings, an excruciating inner yearning for life and self-expression and with all this yet to die. It seems like a hoax…

• Ernest Becker, "The Denial of Death", 1973

In the literature of supernatural horror, a familiar storyline is that of a character who encounters a paradox in the flesh, so to speak, and must face down or collapse in horror before this ontological perversion —something which should not be, and yet is. Most fabled as specimens of a living paradox are the "undead," those walking cadavers greedy for an eternal presence on earth. But whether their existence should go on unendingly or be cut short by a stake in the heart is not germane to the matter at hand. What is exceedingly material resides in the supernatural horror that such beings could exist in their impossible way for an instant. Other examples of paradox and supernatural horror congealing together are inanimate things guilty of infractions against their nature. Perhaps the most outstanding instance of this phenomenon is a puppet that breaks free of its strings and becomes self-mobilized.

[…]

Whether or not there really are manifestations of the supernatural, they are horrifying to us in concept, since we think ourselves to be living in a natural world, which may be a festival of massacres but only in a physical rather than a metaphysical purport. This is why we routinely equate the supernatural with horror. And a puppet possessed of life would exemplify just such a horror, because it would negate all conceptions of a natural physicalism and affirm a metaphysics of chaos and nightmare. It would still be a puppet, but it would be a puppet with a mind and a will, a human puppet—a paradox more disruptive of sanity than the undead. But that is not how they would see it. Human puppets could not conceive of themselves as being puppets at all, not when they are fixed with a consciousness that excites in them the unshakable sense of being singled out from all other objects in creation. Once you begin to feel you are making a go of it on your own—that you are making moves and thinking thoughts which seem to have originated within you—it is not possible for you to believe you are anything but your own master.

• Thomas Ligotti, “The Conspiracy Against the Human Race”, 2010

Why, then, was the human race not wiped out long ago in great, raging epidemics of insanity? Why are there so few individuals who succumb to the pressure of life because their acuity reveals to them more than they can bear?

A consideration of the spiritual history and present state of our species suggests the following answer: most people manage to save themselves by artificially paring down their consciousness.

• Peter Wessel Zapffe, “The Last Messiah”, 1933

Although we typically take our cultural worldview for granted, it is actually a fragile human construction that people spend great energy creating, maintaining, and defending. Since we’re constantly on the brink of realizing that our existence is precarious, we cling to our culture’s governmental, educational, and religious institutions and rituals to buttress our view of human life as uniquely significant and eternal.

• Sheldon Solomon, Jeff Greenberg, Tom Pyszczynski, “The Worm at the Core: On the Role of Death in Life”, 2015

Man is an animal who has to live in a lie in order to live at all.

• Ernest Becker, “Escape From Evil”, 1975

This is actually two questions in one:

1. How do you counter pessimism in yourself?

How do you keep yourself from sliding into cynicism? Seeing the worst in things? Finding fault everywhere? Losing hope?

2. How do you counter pessimism in others?

When someone’s sharing their pessimism with you, it can feel dismissive or even hostile to go against it. It can feel unempathetic to do anything but corroborate or validate their feelings, even if you feel they’re inaccurate or misguided. How do you respond without sliding into pessimism yourself?

I have felt lost recently, I have lost my purpose. If anyone feels the same, what do you do about it? Is there really anything to do about it other than forgetting the dread? I don't like being this pessimistic, but I don't really see a way out of it.