A really long time ago I was introduced to the Evoluent Vertical Mouse. Even though I was only in my early twenties I already had wrist issues and I thought this thing was god send. It was clunky but totally worth it.

These days there are a ton of vertical mice available. Is anyone else into these? I am looking to get a new one now that I'm on the mouse/keyboard a lot again. Do you have a preferred model?

note: If you have wrist issues and are curious, I highly recommend trying one out. One caveat is that the cheap one I got off of amazon recently is a bit too small for a decent sized guy like myself. Filling out your palm seems really important for maximum relief.

I've been curious about making a switch for ergonomics and just lack of space on my desk.

• Do you recommend it for gaming? Any guidance on genres that do or don't work? I mostly play real time and turn based strategy games or point-and-click style games such as Diablo on my computer. I don't generally go in for twitchy FPSes, but I'd like the option.

• Opinions on index vs. thumb?

• How long was the adjustment period to get used to it?

• Any recommendations on good ones to buy?

• Are there any advantages I'm not thinking of besides just being better for my wrist?

• Disadvantages besides, potentially, being less precise than a mouse?

• Are there any tradeoffs with going wireless?

I am replacing my mouse, and I have giant hands. Pretty much every mouse I've ever used has been too small for me, so I would like to finally buy something that fits.

I don't need anything fancy beyond two buttons and a scroll-wheel. It doesn't have to have extra buttons or switchable DPI or anything like that (though I'm not opposed to those either). It'll be used on Linux, and will be my everyday driver. Wired and ergonomic are preferred but not mandatory.

Anyone have any good recommendations?