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43 votes
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Polygon review: Palia is an early access utopia that relies on its regular patches
14 votes -
What did you do this week (and weekend)?
As part of a weekly series, these topics are a place for users to casually discuss the things they did — or didn't do — during their week. Did you accomplish any goals? Suffer a failure? Do...
As part of a weekly series, these topics are a place for users to casually discuss the things they did — or didn't do — during their week. Did you accomplish any goals? Suffer a failure? Do nothing at all? Tell us about it!
14 votes -
Offbeat Fridays – The thread where offbeat headlines become front page news
Tildes is a very serious site, where we discuss very serious matters like unity, elon musk and tortillas. Tags culled from the highest voted topics from the last seven days, if anyone was curious....
Tildes is a very serious site, where we discuss very serious matters like unity, elon musk and tortillas. Tags culled from the highest voted topics from the last seven days, if anyone was curious.
But one of my favourite tags happens to be offbeat! Taking its original inspiration from Sir Nils Olav III, this thread is looking for any far-fetched
offbeatstories lurking in the newspapers. It may not deserve its own post, but it deserves a wider audience!24 votes -
Plan for £100m UK underwater living research facility move forward
12 votes -
The earthquakes in Turkey killed a prolific war crimes investigator, deputy chief of Syria investigations for the Commission for International Justice and Accountability
9 votes -
US government imposes sanctions on five Turkish corporations over dealings with Russia
7 votes -
Study shows US public defenders have significantly more clients than they can adequately represent
27 votes -
Nigerian power grid in ‘total system collapse’. Generation falls to zero, with blackouts across most of Africa’s largest economy
20 votes -
Economist, business professor, digital economy expert Shane Greenstein discusses the US Department of Justice vs Google antitrust case
4 votes -
Who are your favorite Tiny Desk concert musicians? Bob Boilen - Tiny Desk founder is leaving National Public Radio
51 votes -
Douglas B. Lenat - The Ubiquity of Discovery
4 votes -
Fresh Album Fridays: Mitski, Nas, Explosions in the Sky and more
Good morning ~ This is a thread to discuss new album releases that have arrived on our doorstep this week. Feel free to share albums and EPs that have caught your eye and interest! Discussion...
Good morning ~ This is a thread to discuss new album releases that have arrived on our doorstep this week. Feel free to share albums and EPs that have caught your eye and interest!
Discussion Points
What are you looking forward to listen to?
Have you listened to any of these releases?
What are your thoughts?
What have you enjoyed from these artists in the past?Why Friday?
Most (but not all) new LPs release on a Friday, as labels want to give the release a full week of sales before entering the charts.
~~ Feedback on the format welcome!
15 votes -
Veilid — a peer-to-peer network and application framework by Cult of the Dead Cow
26 votes -
The One Piece adventure will continue
24 votes -
As Finland's presidential election gets underway, one key question looks set to dominate – whom do Finns trust to deal with Russia?
7 votes -
About 13,000 workers go on strike seeking better wages and benefits from Detroit’s three automakers
62 votes -
Resident Evil 4 Remake | DLC reveal trailer
11 votes -
Bill Willingham sends Fables into the public domain
39 votes -
Meet the winners of the 2023 Ig Nobel Prizes
21 votes -
Investors can't get enough US debt as Treasury bills are bought at a record pace
16 votes -
Hunter Biden indicted on US federal gun charges
23 votes -
Unity publishes new FAQ implying digital store owners such as Playstation, Xbox, and Nintendo will pay its new fees on behalf of developers
29 votes -
Humanity's current space behavior 'unsustainable,' due to satellite and space junk congestion, European Space Agency report warns
49 votes -
Game Development Post-Unity
18 votes -
The crazy VW Beetles that conquered Antarctica
7 votes -
Intel confirms Thunderbolt 5 name, 120Gbps tech arrives in 2024
15 votes -
San Francisco considers lifting the Ferry Building by seven feet to save it from the sea
15 votes -
Angel's Egg
10 votes -
Investigating how a git repository stores the old versions of files
21 votes -
The Wonderful Story of Henry Sugar | Official trailer
9 votes -
Chromebooks will get updates for ten years
23 votes -
Ludvig Åberg outshines Rory McIlroy in stellar start to PGA Championship at Wentworth
2 votes -
Do droughts make floods worse?
14 votes -
How flexible circuit boards, or FPCs, are made. We're visiting one of JLCPCB's circuit board factories in Shaoguang, China.
5 votes -
How do you get "back on track"? Could use advice.
I have a very long history of mental illness from age 10, and though I've cycled through a lot of explanations the diagnoses that best match my symptoms currently are currently ADHD and CPTSD. I...
I have a very long history of mental illness from age 10, and though I've cycled through a lot of explanations the diagnoses that best match my symptoms currently are currently ADHD and CPTSD. I am medicated for both, and although I am not in active therapy I have also done therapy. I consider my mental health relatively well-managed currently: at least, I am not in any urgent danger of hurting myself and it has been a very long time since I have been. Certainly things could be better but I'm usually functional.
But sometimes I go through these phases, generally 1-3 months long, where my ability to function on a normal level slips dramatically. It never gets to the nightmarish state I was in when I was a teenager, but it becomes hard to... oh, make appointments, do the dishes, walk the dog, just generally deal with the obligations of being an adult. My house is never in GREAT shape but it becomes a disaster. Work performance suffers a lot, my relationships suffer. I also start experiencing emotional PMS symptoms (or perhaps I just lose the ability to suppress them), and while I'm not the type to have "emotional outbursts" I do experience deep and irrational sadness or anger on those days. I also tend to end up dealing with insomnia, which is like a force multiplier on feeling overwhelmed.
It sucks especially because it's like I'm watching myself do it, and I feel as though I don't have enough control over myself to nip it in the bud, and sometimes the damage I do during these times is not fixable at all. It's almost like an unplaceable craving, like there's some thing I'm missing and my subconscious and my body are trying to send me signals, and I just can't interpret them right and figure out what I need.
How I generally get out of these phases is -- well, it's a bit chicken-egg, because the turmoil makes it difficult for me to reach out for help or even do anything to help myself, so to me it seems like sometimes the wave just passes. I'll say, "ok, this time I'll get my shit together", download some new app or whatever, organize my time or tasks via some new fascinating system, and that'll work... but it feels like it's only because I'm "ready" for it to work.
I think it's unlikely I'll find a solution that will work indefinitely to prevent these slips (hooray, novelty-obsessed brain). And anyway - as though it even needs to be said - I'm sulking in the midst of one now, so prevention or reduction tips might be helpful later, but for this moment I'm mostly concerned with getting out once I'm in.
If you have "swingy" mental health, or phases, or waves - what do YOU do about it, if anything? Therapy? Do you change your medication? Do you take a vacation? Commiserate on your favourite internet forums? What works for you?
45 votes -
Star Trek: Lower Decks - S04E01 “Twovix”
8 votes -
Timeline of the history of the web
4 votes -
Aquaman and the Lost Kingdom | Trailer
7 votes -
US researchers employed by federal Housing and Urban Development agency propose study re comparative effectiveness of cash grants vs current system of vouchers for housing assistance
15 votes -
What creative projects have you been working on?
This topic is part of a series. It is meant to be a place for users to discuss creative projects they have been working on. Projects can be personal, professional, physical, digital, or even just...
This topic is part of a series. It is meant to be a place for users to discuss creative projects they have been working on.
Projects can be personal, professional, physical, digital, or even just ideas.
If you have any creative projects that you have been working on or want to eventually work on, this is a place for discussing those.
10 votes -
Natural compound found in plants inhibits deadly fungi
7 votes -
Denmark launches the Laura Maersk, the first container ship to run entirely on green methanol – will save 2.75 million tonnes of CO2 per year
21 votes -
Eight in ten women married to men still take husband’s last name, survey finds
34 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
5 votes -
Weekly megathread for news/updates/discussion of Russian invasion of Ukraine - September 14
This thread is posted weekly on Thursday - please try to post relevant content in here, such as news, updates, opinion articles, etc. Especially significant updates may warrant a separate topic,...
This thread is posted weekly on Thursday - please try to post relevant content in here, such as news, updates, opinion articles, etc. Especially significant updates may warrant a separate topic, but most should be posted here.
If you'd like to help support Ukraine, please visit the official site at https://help.gov.ua/ - an official portal for those who want to provide humanitarian or financial assistance to people of Ukraine, businesses or the government at the times of resistance against the Russian aggression.
13 votes -
Sweden's right-wing government says it will turn its back on plastic bag tax from November 2024
20 votes -
Phenylephrine, a common decongestant in medicines is no better than a placebo when taken orally, says a US FDA advisory panel
by Wes Davis A key cold medicine ingredient is basically worthless The FDA’s 16-member advisory panel unanimously voted yesterday that oral phenylephrine, a common active ingredient in cold...
by Wes Davis
A key cold medicine ingredient is basically worthless
The FDA’s 16-member advisory panel unanimously voted yesterday that oral phenylephrine, a common active ingredient in cold medications, is no better than a placebo for treating congestion.
Link to the article
The call by the panel sets up potential FDA action that could force the removal of certain over-the-counter medications containing the ingredient — including certain formulations of Mucinex, Sudafed, Tylenol, and NyQuil — from store shelves.
But FDA may hold off for many months, pending contested findings by drug makers and other considerations.Data
Newer data from studies the panel says are more consistent with modern clinical trial standards showed phenylephrine simply “was not significantly different from placebo” in the recommended dosage, including trials from 2007 that the FDA had reviewed when considering the drug after a citizen petition prompted it to do so.
Bioavailability
The panel cited the drug’s low bioavailability, a term referring to qualities that allow the drug to be absorbed by the human body, as the main reason the drug should be removed from the market.
Jennifer Schwartzott said the drug “should have been removed from the market a long time ago,” while Dr. Stephen Clement said that although the drug itself isn’t dangerous, its usage by patients should be considered unsafe because it potentially delays actual treatment of disease symptoms.
Alternative
The panel cited pseudoephedrine as an effective alternative though while it’s technically available without a prescription, you must talk to a pharmacist to get it because, in large quantities, it can be used to make methamphetamines.
50 votes -
We're all living on r/MadeMeSmile's Internet Now
77 votes -
China behind ‘largest ever’ digital influence operation
15 votes