When is is okay to give up on making a situation work?

I legitimately ask, as I’ve pretty much given up on most “immediate” family in recent months. As an American federal civilian employee, I found the rhetoric of my immediate family crazy enough to warrant cutting them out of my life. I can’t get beyond their clear contempt for my livelihood. Despite conversations regarding how a certain admin’s policies are making my life worse, I have been told constantly not to complain because it could be worse. So I have “given up” and no longer interact with them. There have been further conversations prior to this, but I don’t think it’s necessarily important to the conversation.

I ask this legitimately, as I am feeling guilt over it, despite the fact that I no longer feel dread or anxiety about it. I haven’t visited immediate family in over 2 months now, despite living within walking distance.

At what point should one continue making attempts to repair to maintain relationships, even familial, and when is it okay to end them?