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    1. What did you do this week (and weekend)?

      As part of a weekly series, these topics are a place for users to casually discuss the things they did — or didn't do — during their week. Did you accomplish any goals? Suffer a failure? Do...

      As part of a weekly series, these topics are a place for users to casually discuss the things they did — or didn't do — during their week. Did you accomplish any goals? Suffer a failure? Do nothing at all? Tell us about it!

      14 votes
    2. Offbeat Fridays – The thread where offbeat headlines become front page news

      Tildes is a very serious site, where we discuss very serious matters like unity, elon musk and tortillas. Tags culled from the highest voted topics from the last seven days, if anyone was curious....

      Tildes is a very serious site, where we discuss very serious matters like unity, elon musk and tortillas. Tags culled from the highest voted topics from the last seven days, if anyone was curious.

      But one of my favourite tags happens to be offbeat! Taking its original inspiration from Sir Nils Olav III, this thread is looking for any far-fetched offbeat stories lurking in the newspapers. It may not deserve its own post, but it deserves a wider audience!

      24 votes
    3. Fresh Album Fridays: Mitski, Nas, Explosions in the Sky and more

      Good morning ~ This is a thread to discuss new album releases that have arrived on our doorstep this week. Feel free to share albums and EPs that have caught your eye and interest! Discussion...

      Good morning ~ This is a thread to discuss new album releases that have arrived on our doorstep this week. Feel free to share albums and EPs that have caught your eye and interest!

      Discussion Points

      What are you looking forward to listen to?
      Have you listened to any of these releases?
      What are your thoughts?
      What have you enjoyed from these artists in the past?

      Why Friday?

      Most (but not all) new LPs release on a Friday, as labels want to give the release a full week of sales before entering the charts.

      ~~ Feedback on the format welcome!

      15 votes
    4. How do you get "back on track"? Could use advice.

      I have a very long history of mental illness from age 10, and though I've cycled through a lot of explanations the diagnoses that best match my symptoms currently are currently ADHD and CPTSD. I...

      I have a very long history of mental illness from age 10, and though I've cycled through a lot of explanations the diagnoses that best match my symptoms currently are currently ADHD and CPTSD. I am medicated for both, and although I am not in active therapy I have also done therapy. I consider my mental health relatively well-managed currently: at least, I am not in any urgent danger of hurting myself and it has been a very long time since I have been. Certainly things could be better but I'm usually functional.

      But sometimes I go through these phases, generally 1-3 months long, where my ability to function on a normal level slips dramatically. It never gets to the nightmarish state I was in when I was a teenager, but it becomes hard to... oh, make appointments, do the dishes, walk the dog, just generally deal with the obligations of being an adult. My house is never in GREAT shape but it becomes a disaster. Work performance suffers a lot, my relationships suffer. I also start experiencing emotional PMS symptoms (or perhaps I just lose the ability to suppress them), and while I'm not the type to have "emotional outbursts" I do experience deep and irrational sadness or anger on those days. I also tend to end up dealing with insomnia, which is like a force multiplier on feeling overwhelmed.

      It sucks especially because it's like I'm watching myself do it, and I feel as though I don't have enough control over myself to nip it in the bud, and sometimes the damage I do during these times is not fixable at all. It's almost like an unplaceable craving, like there's some thing I'm missing and my subconscious and my body are trying to send me signals, and I just can't interpret them right and figure out what I need.

      How I generally get out of these phases is -- well, it's a bit chicken-egg, because the turmoil makes it difficult for me to reach out for help or even do anything to help myself, so to me it seems like sometimes the wave just passes. I'll say, "ok, this time I'll get my shit together", download some new app or whatever, organize my time or tasks via some new fascinating system, and that'll work... but it feels like it's only because I'm "ready" for it to work.

      I think it's unlikely I'll find a solution that will work indefinitely to prevent these slips (hooray, novelty-obsessed brain). And anyway - as though it even needs to be said - I'm sulking in the midst of one now, so prevention or reduction tips might be helpful later, but for this moment I'm mostly concerned with getting out once I'm in.

      If you have "swingy" mental health, or phases, or waves - what do YOU do about it, if anything? Therapy? Do you change your medication? Do you take a vacation? Commiserate on your favourite internet forums? What works for you?

      45 votes
    5. What creative projects have you been working on?

      This topic is part of a series. It is meant to be a place for users to discuss creative projects they have been working on. Projects can be personal, professional, physical, digital, or even just...

      This topic is part of a series. It is meant to be a place for users to discuss creative projects they have been working on.

      Projects can be personal, professional, physical, digital, or even just ideas.

      If you have any creative projects that you have been working on or want to eventually work on, this is a place for discussing those.

      10 votes
    6. Fitness Weekly Discussion

      What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...

      What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?

      5 votes
    7. Weekly megathread for news/updates/discussion of Russian invasion of Ukraine - September 14

      This thread is posted weekly on Thursday - please try to post relevant content in here, such as news, updates, opinion articles, etc. Especially significant updates may warrant a separate topic,...

      This thread is posted weekly on Thursday - please try to post relevant content in here, such as news, updates, opinion articles, etc. Especially significant updates may warrant a separate topic, but most should be posted here.

      If you'd like to help support Ukraine, please visit the official site at https://help.gov.ua/ - an official portal for those who want to provide humanitarian or financial assistance to people of Ukraine, businesses or the government at the times of resistance against the Russian aggression.

      13 votes
    8. Phenylephrine, a common decongestant in medicines is no better than a placebo when taken orally, says a US FDA advisory panel

      by Wes Davis A key cold medicine ingredient is basically worthless The FDA’s 16-member advisory panel unanimously voted yesterday that oral phenylephrine, a common active ingredient in cold...

      by Wes Davis


      A key cold medicine ingredient is basically worthless

      The FDA’s 16-member advisory panel unanimously voted yesterday that oral phenylephrine, a common active ingredient in cold medications, is no better than a placebo for treating congestion.


      Link to the article


      The call by the panel sets up potential FDA action that could force the removal of certain over-the-counter medications containing the ingredient — including certain formulations of Mucinex, Sudafed, Tylenol, and NyQuil — from store shelves.
      But FDA may hold off for many months, pending contested findings by drug makers and other considerations.

      Data

      Newer data from studies the panel says are more consistent with modern clinical trial standards showed phenylephrine simply “was not significantly different from placebo” in the recommended dosage, including trials from 2007 that the FDA had reviewed when considering the drug after a citizen petition prompted it to do so.

      Bioavailability

      The panel cited the drug’s low bioavailability, a term referring to qualities that allow the drug to be absorbed by the human body, as the main reason the drug should be removed from the market.

      Jennifer Schwartzott said the drug “should have been removed from the market a long time ago,” while Dr. Stephen Clement said that although the drug itself isn’t dangerous, its usage by patients should be considered unsafe because it potentially delays actual treatment of disease symptoms.

      Alternative

      The panel cited pseudoephedrine as an effective alternative though while it’s technically available without a prescription, you must talk to a pharmacist to get it because, in large quantities, it can be used to make methamphetamines.

      50 votes
    9. What is something someone has said that stuck with you?

      One time I asked someone what they thought about the phrase "people are temporary" and it ended with them telling me: I don't like saying goodbye to people because I don't know if it's going to be...

      One time I asked someone what they thought about the phrase "people are temporary" and it ended with them telling me:

      I don't like saying goodbye to people because I don't know if it's going to be the last time.

      That just stuck with me and really got me thinking how precious our time is.

      54 votes