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35 votes
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Ten open challenges/research directions in LLM research
7 votes -
What does any of this have to do with physics?
41 votes -
Evidence undermines "Rapid Onset Gender Dysphoria" claims
41 votes -
Learning how to garden a forest - discussion of methods to prevent wildfire
12 votes -
Closing down an icon: Although Arecibo Observatory is slated to become an education center, astronomers hope research might one day return to the site
13 votes -
Transgender and nonbinary patients have no regrets about top surgery, small study finds
61 votes -
Estimating the association between Facebook adoption and well-being in seventy-two countries
5 votes -
Scripps Institution of Oceanography’s FLIP vessel decommissioned after sixty years
10 votes -
What are your favourite research papers?
I've been diving into Derek Parfit's thought-provoking "Why Anything? Why This?" and exploring Weber's fascinating "Sociology of Religion." It's ignited my curiosity about which research papers or...
I've been diving into Derek Parfit's thought-provoking "Why Anything? Why This?" and exploring Weber's fascinating "Sociology of Religion." It's ignited my curiosity about which research papers or articles have really resonated with you? I'm excited to broaden my reading horizons and discover some impactful reads!
14 votes -
Researchers, how do you take notes on the papers which you read?
I've been struggling with finding a good workflow for taking notes on the journal articles which I read. I collate articles using Zotero, yet its in-built notetaking features (and comment scraping...
I've been struggling with finding a good workflow for taking notes on the journal articles which I read. I collate articles using Zotero, yet its in-built notetaking features (and comment scraping from PDFs) is quite poor. So, my alternative so far has been to write up notes by hand, but this is pretty cumbersome and makes it take some time to refer to my notes. My approach is clearly not effective!
How do you take notes on the papers which you read? Do you prefer to use written notes, or do you type your notes? In any case, what is your preferred means of storing and categorising your notes? And are there particular software which you use, if you opt for typed notes? (At present, I use an A5 notebook. Yet, this is not alphabetised or organised by topic, which compounds my struggles.)
25 votes -
We need more research on how CO2 affects cognition
8 votes -
Twitter threatens legal action against US nonprofit that tracks hate speech
113 votes -
Five tips for using PubPeer to investigate scientific research errors and misconduct
8 votes -
Pay dirt for ice core scientists in East Greenland as they reach bedrock
24 votes -
That essential morning coffee may be a placebo
42 votes -
IAMA 3rd year Ph.D. student researching the cell biology of the Rice Blast fungus, Magnaporthe oryzae, and preparing for my candidacy qualifying exam. AMA.
Hi Tilders! I am new here, but my experience with the community thus far has encouraged me to post an AMA. I've specifically decided to post this AMA in ~talk rather than ~science for more...
Hi Tilders! I am new here, but my experience with the community thus far has encouraged me to post an AMA. I've specifically decided to post this AMA in ~talk rather than ~science for more exposure, and because I am hoping to field questions ranging from scientifically well-read to less-read, technical to curious, why care to who cares, and everything in between.
I won't be posting "verifying proof", because like many of you, I love my anonymity here. However, I will include peer-reviewed citations to question answers when I feel it necessary. I will do my best to share free-access articles, but this won't always be possible. If I link an article of interest to you that is paid-access, message me; maybe, I may be able to get a copy to you. Also, please be patient for my replies. Even though it is summer where I am, I am still busy in the lab and thoughtful responses take time.
Here is a brief background on the Rice Blast fungus to help get the conversation started:
Rice is an important staple food consumed by nearly half of the global population Khush. 2005. From 10 - 30% of the annual rice harvest is lost to disease caused by Magnaporthe oryzae, which is enough rice to feed greater than 60 million people Skamnioti and Gurr. 2009. To cause infection, a three-celled asexual spore called a conidium attaches to the rice plant's leaves, stems, and even roots. Once attached, a germ tube emerges from one of the three cells and grows along the surface of the plant. Hydrophobic molecules on the plant surface, called hydrophobins, induce a developmental change in the growing germ tube. The growing germ tube tip begins to form a dome-shaped structure called the appressorium. This specialized structure swells and generates up to 80 Mpa of pressure, enough to penetrate kevlar. A penetration peg penetrates the plant cell tissue, and bulbous invasive hyphae colonize the plant cell tissue. The fungus keeps the invaded plant cell alive, while it consumes its nutrients, with the plant cell dying only when the invading growth moves to an adjacent cell Cruz-Mireles et al. 2021. Schematic.
The Rice Blast research community focuses on all stages of its development. My work is focused on nuclear division during different developmental stages, and I am specifically working on understanding which and how motor proteins are involved in nuclear division in this fungus. Understanding the nuclear dynamics and the involved machinery will hopefully open avenues for controlling the plant infection and reducing the global crop loss.
I hope you all find Rice Blast interesting, and I hope I will be able to answer many interesting questions!
40 votes -
Medical researchers report that the workers who make quartz countertops are dying of lung disease at a young age
31 votes -
Cochrane UK closes because funding has ended
11 votes -
Researchers are trying to unravel the mystery of snow that falls but never shows up in the Colorado river
13 votes -
Computer chip with built-in human brain tissue gets military funding
39 votes -
ChatGPT can be broken by entering these strange words, and nobody is sure why
56 votes -
Stanford University president resigns over manipulated research, will retract at least three papers
47 votes -
New study finds Covid can infect the liver
13 votes -
Hustle culture kills happiness. Here’s how to escape it. | Laurie Santos
9 votes -
Parrots taught to video call each other become less lonely, finds research
10 votes -
Total recall: A brilliant memory helps chickadees survive
9 votes -
A one-of-a-kind bat research facility coming to Fort Collins has CSU scientists fighting misinformation
8 votes -
Put food on the edge of microwave plate instead of the middle
23 votes -
More evidence that gas stoves produce suprisingly large amounts of harmful pollutants
82 votes -
Meltwater is hydro-fracking Greenland's ice sheet through millions of hairline cracks – destabilizing its internal structure
10 votes -
Why depression after traumatic brain injury is distinct — and less likely to respond to standard treatment
Traumatic brain injury multiplies the risk of major depression eightfold. While the emotional trauma of whatever caused such deep damage may be understandable, from a blast in a war zone to a blow...
Traumatic brain injury multiplies the risk of major depression eightfold. While the emotional trauma of whatever caused such deep damage may be understandable, from a blast in a war zone to a blow on the playing field, there’s a physiological component, too, that neuroscientists have long suspected but have been unable to identify.
“As clinicians, a lot of us had a gut feeling that [TBI-associated depression] is a different disease,” said Shan Siddiqi, a Harvard Medical School assistant professor of psychiatry and a clinical neuropsychiatrist at Brigham and Women’s Hospital in Boston. “Why did nobody detect it before? I think the reason is because unlike other psychiatric disorders, TBI caused a sort of structural reorganization of the brain.”
https://www.statnews.com/2023/07/06/depression-after-traumatic-brain-injury/
16 votes -
Stressed rattlesnakes found to calm down in the company of a nearby 'friend'
11 votes -
Having an out-of-body experience? Blame this sausage-shaped piece of your brain
10 votes -
Superconductor chaos
8 votes -
Injection of kidney protein improves working memory in monkeys
9 votes -
There’s finally a psychedelic caucus in congress — here’s what they’re doing
21 votes -
Golden age of medicine
18 votes -
Aspartame sweetener used in Diet Coke a possible carcinogen, World Health Organization's cancer research agency to say - sources
40 votes -
Aspartame may be declared a possible carcinogen by IARC
56 votes -
Study shows that US public pension funds would be $21 billion richer had they divested from fossil fuels a decade ago
17 votes -
The latest dangerous conspiracy theory: That conspiracy theory research is part of a big conspiracy
30 votes -
An inhaled Covid vaccine booster was more than five-fold effective for inducing neutralizing antibodies at 28-days, and more durable at one-year, than shots, vs Omicron BA.5 in a randomized trial
18 votes -
Why it took us thousands of years to see the colour violet
6 votes -
The advent of sunglasses
9 votes -
Why Koko the gorilla couldn't talk
13 votes -
Everyone in the world has twenty-four hours, but how do they spend their time? This is what the average human day looks like.
14 votes -
UK to stop administering puberty blockers to adolescents
46 votes -
Controversial research project in Norway on whales' hearing suspended after a whale drowns
8 votes -
The first few moments of an explosion can't be simulated yet. But there's a team at the University of Sheffield working on it.
12 votes