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    4. Inside the very strange, very expensive race to “de-age”

      ~life.men Text 1111 words
      Whizy Kim The Rejuvenation Olympics, an online leaderboard launched by tech millionaire Bryan Johnson earlier this year, takes the rivalry of the rich to the next level. The game? “Reversing” your...

      Whizy Kim

      The Rejuvenation Olympics, an online leaderboard launched by tech millionaire Bryan Johnson earlier this year, takes the rivalry of the rich to the next level. The game? “Reversing” your age

      Link to the article

      Participants compete not on physical abilities but on how quickly and by how much they can slow their “biological age.”

      Competitors do this mostly by adjusting their diets (like which macronutrients and supplements they consume), being physically active, and retesting their “age” regularly. They’re not actually reverting to a more youthful version of themselves — that’s not biologically possible. Rather, these competitors are racing to see who can age the slowest; as the Rejuvenation Olympics website quips, “You win by never crossing the finish line.”

      Some participants

      Steve Aoki, the DJ and heir to the Benihana restaurant chain, appears toward the bottom of the site’s “absolute” ranking, which reflects the 25 competitors with the lowest rate of aging.

      The biohacker Ben Greenfield makes the list, too, as does millionaire and longevity science advocate Peter Diamandis. Most of the top 25 names, however, don’t spark immediate recognition, and some are anonymous.

      Right now, tech millionaire Bryan Johnson, who is 46 years old, is leading. But 46 is just what competitors describe as Johnson’s “chronological age,” which means, simply, the years that have passed since his birth date.

      He has claimed that he eats 70 pounds of vegetables per month, most of it pureed. He receives blood transfusions from his 17-year-old son. He wears a red-light cap that’s supposed to stimulate hair growth. His body fat once fell to a dangerous 3 percent (though it has since bumped up a few percentage points).

      Twitter founder Jack Dorsey is renowned for his eccentric wellness habits; he eats one meal a day, meditates for at least two hours daily, and has a penchant for ice baths. For a while, Steve Jobs was a “fruitarian” — as in, only ate fruit.

      Lifestyles of ultrarich

      Such extremes are common among the ultrarich, and particularly the Silicon Valley set, a crowd known for its obsession with making moonshot ideas into reality.

      The wealthy indulge in countless health trends of varying dubiousness, whether it’s getting IV drips to reduce hangovers, hyperbaric oxygen therapy, implanting devices in the body to monitor health and live longer, even injecting themselves with young blood (a treatment called parabiosis, which Johnson is receiving). This year alone, Johnson will reportedly spend at least $2 million on reducing his biological age.

      Society treats them as idols, geniuses whose savvy has vaulted them into the 0.0001 percent of the wealthiest people on Earth. It’s a small hop from there to believing they’d also be savvier than the rest of us about turning back the clock.

      Investing in de-aging

      Last year, according to a report from the news and market analysis site Longevity. Technology, more than $5 billion in investments poured into longevity-related companies worldwide, including from some big-name tech founders and investors. Many of these companies are aiming to prolong life by focusing on organ regeneration and gene editing.

      The buzzy life extension company Altos Labs, which researches biological reprogramming — a way to reset cells to pliable “pluripotent stem cells” — launched last year with a whopping $3 billion investment, and counts internet billionaire Yuri Milner and, reportedly, Amazon founder Jeff Bezos among its patrons. Bezos was also an investor in the anti-aging startup Unity Biotechnology.

      OpenAI founder Sam Altman, meanwhile, recently invested $180 million in Retro Biosciences, a company vying to add a decade to the human lifespan.

      Some of the most famous names in the death-defying sector are old: Calico Labs, a longevity-research subsidiary of Alphabet, was launched by then-Google CEO Larry Page in 2013.

      Tally Health, a new biotech company co-founded by Harvard scientist David Sinclair — who is something of a celebrity in the longevity community — boasts some Hollywood A-list investors: John Legend, Gwyneth Paltrow, Ashton Kutcher, Pedro Pascal, and Zac Efron.

      Possibility of de-aging

      “It’s not possible to reverse your age,” Stuart Jay Olshansky, an aging expert and professor of epidemiology and biostatistics at the University of Illinois Chicago, tells Vox. “There’s validity to some of the work that’s going on in epigenetics that may be telling us something about the rate of aging. It’s not yet telling us about longevity.”

      No two people age in the exact same way. Discrete from chronological age, “biological age” is the attempt to capture the often invisible difference through epigenetic gene expression, the state of someone’s organs, their immune system, and more.

      A 40-year-old with a history of heavy drinking and smoking, for example, may have a higher biological age than someone who never drinks or smokes. (In 2018, a Dutch man even complained that he ought to be able to change his legal age to match his biological age.)

      Johnson again

      Johnson, who made his hundreds of millions after selling a payments platform he developed to eBay in 2013, has become renowned not for what he’s invented, sold, or designed, as is the case for many other Silicon Valley entrepreneurs, but for the unimaginably strict lifestyle he leads.

      According to his website and the many interviews he has given, he exerts constant vigilance over the 78 organs of the human body, consistently tracking everything from BMI to brain white matter. Johnson is often described as the “most measured man in human history.”

      The point isn’t merely being healthy. It’s laser-precision optimization of his health.

      Johnson, for example, never eats pizza or drinks alcohol. It’s simply not a part of his algorithm. “I was just a slave to myself and my passions and my emotions and my next desire,” he said in an interview with Vice Motherboard. That doesn’t mean he never stumbles, but when he does, he calls it an “infraction,” as though he has committed a minor crime.

      Leaderboard

      Johnson tops the Rejuvenation Olympics leaderboard; he created the game along with Oliver Zolman — who leads Johnson’s team of 30-plus doctors and other health experts — and TruDiagnostic, an epigenetics lab based in Kentucky that provides the biological age test kits that participants in the Olympics must submit. The cheaper version costs $229. The more expensive one, at $499, provides more data on your results, including how habits like smoking or drinking alcohol have impacted a person’s aging speed.

      Ultramarathon

      It’s a contest that participants hope never ends — the most ultra of ultramarathons. The most dedicated members in the longevity community are, in essence, spending their lives obsessing over living. Says Lustgarten: “I plan on doing this for at least the next 70-plus years.”

      27 votes

    14. Online payment methods, are there significant upsides or downsides of one vs another?

      ~tech Ask (advice)
      Specifically this week I have to choose whether to create an account with paypal, cashapp or venmo but I am also interested in a broader discussion including other apps. Any advice or information...

      Specifically this week I have to choose whether to create an account with paypal, cashapp or venmo but I am also interested in a broader discussion including other apps. Any advice or information would be welcome.

      14 votes

    18. TV Tuesdays Free Talk

      ~tv Ask (survey)
      Have you watched any TV shows recently you want to discuss? Any shows you want to recommend or are hyped about? Feel free to discuss anything here. Please just try to provide fair warning of...

      Have you watched any TV shows recently you want to discuss? Any shows you want to recommend or are hyped about? Feel free to discuss anything here.

      Please just try to provide fair warning of spoilers if you can.

      8 votes

    25. Fresh Album Fridays: Mitski, Nas, Explosions in the Sky and more

      ~music Ask
      Good morning ~ This is a thread to discuss new album releases that have arrived on our doorstep this week. Feel free to share albums and EPs that have caught your eye and interest! Discussion...

      Good morning ~ This is a thread to discuss new album releases that have arrived on our doorstep this week. Feel free to share albums and EPs that have caught your eye and interest!

      Discussion Points

      What are you looking forward to listen to?
      Have you listened to any of these releases?
      What are your thoughts?
      What have you enjoyed from these artists in the past?

      Why Friday?

      Most (but not all) new LPs release on a Friday, as labels want to give the release a full week of sales before entering the charts.

      ~~ Feedback on the format welcome!

      15 votes

    44. Which board games have you been playing this week? (to 13 September)

      ~games.tabletop Ask (survey)
      Time to share your weekly board gaming. For me it consisted of a game of Aquanauts at a monthly gathering I've only attended for the second time. The host of the group posted about his new group...

      Time to share your weekly board gaming.

      For me it consisted of a game of Aquanauts at a monthly gathering I've only attended for the second time. The host of the group posted about his new group in a village hall in the middle of nowhere (UK) over on Reddit. Well the middle of nowhere turned out to be not far from where I live so I've been trying to make it when I can ever since.

      Aquanauts was published by a UK publisher Inside the Box Games (best known for Sub Terra) but they went bust recently and another company stepped in and fulfilled the Kickstarter. The game is a basic worker placement, where you're sending your robotic submersibles (workers) out to collect or convert resources. What makes it interesting is that the worker spots are linked, and playing a spot linked to another that has a player worker on it scores you both a bonus resource. You can also build tiles on your player board to similarly receive or convert goods during the income phase. Other than that, you're trying to load up a submarine with the correct resources to score contract cards, and there's a degree of hedging your bets as the person who takes the final slot on the submarine gets to choose the order in which the players claim contracts. It's a fairly good game, fun enough on first play but largely unmemorable.

      Tonight I got in a game of Carnegie. This is a great game that sees you building up your office with departments, staffing them and sending your workers on missions to build buildings across the map of the USA, linking cities. I royally screwed up my first turn and spent several rounds trying to recover which left me way behind on points. Great game with a lot to think about but which neither takes too long to teach or play.

      What have you all been playing?

      7 votes

    47. What did you do this week (and weekend)?

      ~talk Ask (survey)
      As part of a weekly series, these topics are a place for users to casually discuss the things they did — or didn't do — during their week. Did you accomplish any goals? Suffer a failure? Do...

      As part of a weekly series, these topics are a place for users to casually discuss the things they did — or didn't do — during their week. Did you accomplish any goals? Suffer a failure? Do nothing at all? Tell us about it!

      14 votes