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9 votes
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Game recommendations, specifically
This is a thread for game recommendations, but not just any standard game recommendations. This is a thread for game recommendations where you have a very specific thing that you're looking for....
This is a thread for game recommendations, but not just any standard game recommendations.
This is a thread for game recommendations where you have a very specific thing that you're looking for.
Maybe you're looking for a certain type of experience that can't easily be summarized with genres and tags. Maybe you're looking for a game that will evoke a particular feeling that's hard to put into words.
Whatever you're looking for, share your desired specificity below, and let people try to recommend games that fit it.
58 votes -
US Food and Drug Administration approves cure for sickle cell disease, the first treatment to use gene-editing tool CRISPR
49 votes -
Ren - Wicked Ways (2023)
8 votes -
I made a majestic (reverse) centaur
13 votes -
Reports/surveys like The Trevor Project report for other populations?
Hey folks, I have been following The Trevor Project's survey for a few years now and their 2023 one is just presented in a fantastic, easy to read and understand way so I think it's a great...
Hey folks, I have been following The Trevor Project's survey for a few years now and their 2023 one is just presented in a fantastic, easy to read and understand way so I think it's a great resource and worth sharing
The Trevor Project 2023 Survey on Mental Health in LGBTQ young people
BUT, I'm also looking for similar reports focusing on other minoritized populations in particular, or (whether in part or in full) focusing on the age ranges covering college students. I'm struggling to find something nearly so comprehensive, but I'm also not sure I'm looking in the right way. The Steve Fund seems to be a great resource for mental health for students of color, for example, but doesn't have obviously available data like this
10 votes -
What have you been listening to this week?
What have you been listening to this week? You don't need to do a 6000 word review if you don't want to, but please write something! If you've just picked up some music, please update on that as...
What have you been listening to this week? You don't need to do a 6000 word review if you don't want to, but please write something! If you've just picked up some music, please update on that as well, we'd love to see your hauls :)
Feel free to give recs or discuss anything about each others' listening habits.
You can make a chart if you use last.fm:
http://www.tapmusic.net/lastfm/
Remember that linking directly to your image will update with your future listening, make sure to reupload to somewhere like imgur if you'd like it to remain what you have at the time of posting.
10 votes -
Exodus (from the original development team behind Mass Effect) | Reveal trailer
26 votes -
The story of Bruce Springsteen's #1 guitar
4 votes -
Finnish study shows that there is little direct effect of “leisure time physical activity” on lifespan – what makes this study different from others, and is it right?
13 votes -
Despite new Respiratory Syncytial Virus shots, most older US adults remain unvaccinated
13 votes -
What did you do this week (and weekend)?
As part of a weekly series, these topics are a place for users to casually discuss the things they did — or didn't do — during their week. Did you accomplish any goals? Suffer a failure? Do...
As part of a weekly series, these topics are a place for users to casually discuss the things they did — or didn't do — during their week. Did you accomplish any goals? Suffer a failure? Do nothing at all? Tell us about it!
7 votes -
The Game Awards 2023 winners: The full list
26 votes -
Building a home media server on a budget
Hi I figured before I start venturing into other forums dedicated to this sort of thing, I'd ask here on Tildes since I'm at least comfortable with the community and how helpful they can be here....
Hi
I figured before I start venturing into other forums dedicated to this sort of thing, I'd ask here on Tildes since I'm at least comfortable with the community and how helpful they can be here.
I'm tired of all of the subscription services I have, movies and TV shows disappearing from them, buying a film on Prime and only being able to watch it offline through a specific app. Even then, half the time we're watching comfort TV shows that we have on DVD already (X-Files and Friends for instance).
So I figured that building a home media server would give me the chance to cut the cord with a couple of these services and allow us to start using and controlling our own data again.
I have a budget of around £300 (I could perhaps push to £400 if needed) and I'm honestly not sure at all where to start. I have knowledge on how to build brand new, medium to high end gaming PCs as I've done it since I was in my late teens and built my first PC with the wages from my very first job but building a budget minded PC for use as a home media server goes completely over my head.
I've noticed that a lot of the pre-built NAS or media server boxes are very expensive so my first thought was to buy a refurbed workstation or small form factor PC that has enough "oomph" to do the trick but I don't know what ones to even start looking at and then I start to feel a little bit out of my comfort zone.
Things like getting the right CPU in these refurbed machines that offers the features I'm looking for like hardware transcoding etc., integrated GPU's, ensuring there's enough SATA ports for multiple hard drives and an SSD for a boot drive, and then to top it all off ensuring that while achieving these features the thing shouldn't draw too much power when idling as it'll be on for long stretches of time, if not left on 24/7.
I've also got no knowledge of Linux, I've never even looked at it but if it's genuinely easy enough (for someone with next to no Linux experience) then I'd be happy to give it a shot if it offers better performance compared to using Windows 10 or something.
All the server will be used for is watching TV shows, perhaps the odd film, listening to a bit of music perhaps and the odd podcast now and again. Simultaneous streaming will be fairly minimal, perhaps 2 streams as me or my partner watch one thing and our daughter watches another on her tablet. In regards to streaming outside the house that will also be almost non-existent, perhaps, again our daughter watching a kids TV show like Pokemon or Fireman Sam on her tablet when we're out but me and my partner don't tend to watch anything when we're outside the house, certainly not TV shows or movies anyway.
Redundancy isn't something I'm too horrendously worried about, I wouldn't be storing anything like photos that we wouldn't want to lose on it and while it'd be annoying, losing a drive with TV shows or films on it wouldn't be the end of the world.
Any help would be massively appreciated, thanks.
36 votes -
Lotta Wenglén – Riding High (2023)
2 votes -
Starfield analysis | A quick retrospective
12 votes -
What is a classical music piece you like? And why?
What is a classical music piece you enjoy and what do you like about it? Maybe we can help each other find new classical music or even different styles of classical music to listen to. I like...
What is a classical music piece you enjoy and what do you like about it? Maybe we can help each other find new classical music or even different styles of classical music to listen to. I like classical music a lot but I'm far from well versed in the different periods or much more than the most famous composers and performers.
One (far from obscure) piece I like a lot is Paganini's Violin Concerto No. 1. It is full of explosive energy and the diversity and emotion of the violin part always amazes me.
And bonus question: how do you listen to classical music? I primarily listen to the local classical music radio station but occasionally attend concerts.
41 votes -
Issues with NGS Library Prep
Greetings Folks, I apologize if this is the wrong spot for this but I'd like to cast a net to see if I can get any additional thoughts or help. I recently started a new job as NGS Library Prep...
Greetings Folks, I apologize if this is the wrong spot for this but I'd like to cast a net to see if I can get any additional thoughts or help.
I recently started a new job as NGS Library Prep Tech - sadly I had only begun training on this briefly at my last position but only got an introduction to Speed/Mag Bead clean up. I was hired because the lab is growing quickly and has had issues with organizational stuff in the past and that is my strong suit (my last position I did a lot of clonal DNA / miniprep stuff as far as the wet work went).
The person I was replacing at my new job was only there for two days and didn't really help a whole lot other than hand me a haphazardly written protocol and said "practice by cleaning ladders at different bead concentrations and running them on a gel."
Did that and was told they look good.
Fast forward to using actual samples: There were a set that needed to be redone because the final pool was lost. When I did my first qubit quants after the post PCR speed bead clean up I noticed that the quant concentrations were ~80% less than what they had been previously.
Today I have some remaining sample that I can push through PCR, my plan is to quant 8 out of the 53 samples of the pre / post PCR plate and then again after I do clean up.
As far as clean up goes I had been trying to do the whole plate at once, but I'm going to go back to just completing a column at a time to ensure my timing is better.
Are there particular spots in the Speed / Mag Bead clean up process that I should be aware that I could be washing away / losing DNA?
Do people have any tips on how to be more 'sure footed' in this process?
Ways that I can better practice and say "yup, I've got this!"?
Thanks for the help, and if this should be posted somewhere else please let me know, but as this is 'science' related I thought it fit best here.
7 votes -
Offbeat Fridays – The thread where offbeat headlines become front page news
Tildes is a very serious site, where we discuss very serious matters like plagiarism, greedflation and grand theft auto.6. Tags culled from the highest voted topics from the last seven days, if...
Tildes is a very serious site, where we discuss very serious matters like plagiarism, greedflation and grand theft auto.6. Tags culled from the highest voted topics from the last seven days, if anyone was half interested.
But one of my favourite tags happens to be offbeat! Taking its original inspiration from Sir Nils Olav III, this thread is looking for any far-fetched
offbeatstories lurking in the newspapers. It may not deserve its own post, but it deserves a wider audience!8 votes -
Light No Fires (from the makers of No Man's Sky) | Official reveal trailer
30 votes -
Fresh Album Fridays: Nicki Minaj, Neil Young, Blu and more
Good morning ~ This is a thread to discuss new album releases that have arrived on our doorstep this week. Feel free to share albums and EPs that have caught your eye and interest. Discussion...
Good morning ~ This is a thread to discuss new album releases that have arrived on our doorstep this week. Feel free to share albums and EPs that have caught your eye and interest.
Discussion Points
What are you looking forward to listen to?
Have you listened to any of these releases?
What are your thoughts?
What have you enjoyed from these artists in the past?Why Friday?
Most (but not all) new LPs/EPs release on a Friday, as labels want to give the release a full week of sales before entering the charts.
~~ Feedback on the format welcome
9 votes -
Entry level IEM earbuds recommendations?
So I've just been using basic earbuds my whole life, never felt like spending big bucks on good headphones. Recently though, I've been really interested in what I've been hearing about IEMs....
So I've just been using basic earbuds my whole life, never felt like spending big bucks on good headphones. Recently though, I've been really interested in what I've been hearing about IEMs. Youtubers and forum users have been name dropping a few of them, such as Moondrop Chu/Chu II, Salnotes Zero, etc. So I looked them up, and was shocked to find how cheap they are. They're like $20, in the same price range as the crappy earbuds I buy anyways! These kind of headphones seem like a whole world I know nothing about, with pros and cons I don't fully understand, so what would be the best recommendation for a first set?
23 votes -
Day 8: Haunted Wasteland
Today's problem description: https://adventofcode.com/2023/day/8 Please post your solutions in your own top-level comment. Here's a template you can copy-paste into your comment to format it...
Today's problem description: https://adventofcode.com/2023/day/8
Please post your solutions in your own top-level comment. Here's a template you can copy-paste into your comment to format it nicely, with the code collapsed by default inside an expandable section with syntax highlighting (you can replace
pythonwith any of the "short names" listed in this page of supported languages):<details> <summary>Part 1</summary> ```python Your code here. ``` </details>12 votes -
Monster Hunter Wilds | World premiere trailer at The Game Awards 2023
26 votes -
Tales of Kenzera: ZAU | Official reveal trailer
5 votes -
Black Myth: Wukong | Official release date trailer
13 votes -
Reddit moderators of r/law and r/scotus filed an amicus brief in US Supreme Court first amendment case Moody v NetChoice LLC
62 votes -
GamersNexus' "Mega Charts" for PC parts
11 votes -
How Russia punched an $11 billion hole in the West’s oil sanctions
17 votes -
Tildes Minecraft Survival Bi-Weekly Thread
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25 votes -
Metaphor: ReFantazio — The Royal Tournament | Trailer
5 votes -
OD | TGA 2023 teaser trailer
3 votes -
Euclidea - interactive geometric puzzles
7 votes -
God of War Ragnarök: Valhalla | Reveal trailer (PS5 & PS4 games)
13 votes -
Dave the Diver x Dredge Crossover | Trailer
18 votes -
Windblown | Announcement trailer
5 votes -
A pregnant woman in Texas whose fetus has trisomy 18 was granted a court order for an abortion
61 votes -
Danish parliament has voted to ban the burning of religious scriptures after a series of Qur’an desecrations in the country and neighbouring Sweden
26 votes -
Bluesky says it will allow users to opt out of the public web interface after backlash
23 votes -
Green Day - Dilemma (2023)
4 votes -
AFI Awards film top ten: ‘Barbie’, ‘Oppenheimer’, ‘Maestro’, ‘Killers Of The Flower Moon’ among org’s best of 2023
9 votes -
Shutters: What you need to know to avoid mistakes (2017)
7 votes -
The story of electronics (2010)
7 votes -
Amsterdam to cut speed limits 40% to improve road safety
46 votes -
Climate adaptation in no-man's land: Bridging the conflict-climate gap
4 votes -
The rise and fall (and rise and fall) of Venezuela (2019)
7 votes -
Shocking study discovers bottlenose dolphins possess electric sixth sense
11 votes -
What creative projects have you been working on?
This topic is part of a series. It is meant to be a place for users to discuss creative projects they have been working on. Projects can be personal, professional, physical, digital, or even just...
This topic is part of a series. It is meant to be a place for users to discuss creative projects they have been working on.
Projects can be personal, professional, physical, digital, or even just ideas.
If you have any creative projects that you have been working on or want to eventually work on, this is a place for discussing those.
19 votes -
GM’s hydrogen ‘power cubes’ will be used in cement mixers and terminal tractors
15 votes -
Fitness Weekly Discussion
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started...
What have you been doing lately for your own fitness? Try out any new programs or exercises? Have any questions for others about your training? Want to vent about poor behavior in the gym? Started a new diet or have a new recipe you want to share? Anything else health and wellness related?
10 votes